Literature DB >> 17229695

The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP.

Magnus Monné1, Alan J Robinson, Christoph Boes, Michael E Harbour, Ian M Fearnley, Edmund R S Kunji.   

Abstract

Members of the mitochondrial carrier family have been reported in eukaryotes only, where they transport metabolites and cofactors across the mitochondrial inner membrane to link the metabolic pathways of the cytosol and the matrix. The genome of the giant virus Mimiviridae mimivirus encodes a member of the mitochondrial carrier family of transport proteins. This viral protein has been expressed in Lactococcus lactis and is shown to transport dATP and dTTP. As the 1.2-Mb double-stranded DNA mimivirus genome is rich in A and T residues, we speculate that the virus is using this protein to target the host mitochondria as a source of deoxynucleotides for its replication.

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Year:  2007        PMID: 17229695      PMCID: PMC1866048          DOI: 10.1128/JVI.02386-06

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  33 in total

1.  TEXshade: shading and labeling of multiple sequence alignments using LATEX2 epsilon.

Authors:  E Beitz
Journal:  Bioinformatics       Date:  2000-02       Impact factor: 6.937

2.  Probability-based protein identification by searching sequence databases using mass spectrometry data.

Authors:  D N Perkins; D J Pappin; D M Creasy; J S Cottrell
Journal:  Electrophoresis       Date:  1999-12       Impact factor: 3.535

3.  A giant virus in amoebae.

Authors:  Bernard La Scola; Stéphane Audic; Catherine Robert; Liang Jungang; Xavier de Lamballerie; Michel Drancourt; Richard Birtles; Jean-Michel Claverie; Didier Raoult
Journal:  Science       Date:  2003-03-28       Impact factor: 47.728

Review 4.  Lactococcus lactis as host for overproduction of functional membrane proteins.

Authors:  Edmund R S Kunji; Dirk-Jan Slotboom; Bert Poolman
Journal:  Biochim Biophys Acta       Date:  2003-02-17

5.  Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside.

Authors:  Eva Pebay-Peyroula; Cécile Dahout-Gonzalez; Richard Kahn; Véronique Trézéguet; Guy J-M Lauquin; Gérard Brandolin
Journal:  Nature       Date:  2003-11-06       Impact factor: 49.962

6.  Laboratory infection of a technician by mimivirus.

Authors:  Didier Raoult; Patricia Renesto; Philipe Brouqui
Journal:  Ann Intern Med       Date:  2006-05-02       Impact factor: 25.391

7.  Predicting subcellular localization of proteins based on their N-terminal amino acid sequence.

Authors:  O Emanuelsson; H Nielsen; S Brunak; G von Heijne
Journal:  J Mol Biol       Date:  2000-07-21       Impact factor: 5.469

8.  Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functions.

Authors:  K S Echtay; E Winkler; M Bienengraeber; M Klingenberg
Journal:  Biochemistry       Date:  2000-03-28       Impact factor: 3.162

9.  Identification and functional reconstitution of yeast mitochondrial carrier for S-adenosylmethionine.

Authors:  C M T Marobbio; G Agrimi; F M Lasorsa; F Palmieri
Journal:  EMBO J       Date:  2003-11-17       Impact factor: 11.598

Review 10.  Unusual life style of giant chlorella viruses.

Authors:  James L Van Etten
Journal:  Annu Rev Genet       Date:  2003       Impact factor: 16.830

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  13 in total

1.  Unique genes in giant viruses: regular substitution pattern and anomalously short size.

Authors:  Hiroyuki Ogata; Jean-Michel Claverie
Journal:  Genome Res       Date:  2007-07-25       Impact factor: 9.043

2.  The polyadenylation site of Mimivirus transcripts obeys a stringent 'hairpin rule'.

Authors:  Deborah Byrne; Renata Grzela; Audrey Lartigue; Stéphane Audic; Sabine Chenivesse; Stéphanie Encinas; Jean-Michel Claverie; Chantal Abergel
Journal:  Genome Res       Date:  2009-04-29       Impact factor: 9.043

Review 3.  Adenine nucleotide transporters in organelles: novel genes and functions.

Authors:  Javier Traba; Jorgina Satrústegui; Araceli del Arco
Journal:  Cell Mol Life Sci       Date:  2011-01-05       Impact factor: 9.261

4.  mRNA deep sequencing reveals 75 new genes and a complex transcriptional landscape in Mimivirus.

Authors:  Matthieu Legendre; Stéphane Audic; Olivier Poirot; Pascal Hingamp; Virginie Seltzer; Deborah Byrne; Audrey Lartigue; Magali Lescot; Alain Bernadac; Julie Poulain; Chantal Abergel; Jean-Michel Claverie
Journal:  Genome Res       Date:  2010-04-01       Impact factor: 9.043

5.  Physiological adaptation of the bacterium Lactococcus lactis in response to the production of human CFTR.

Authors:  Anton Steen; Elena Wiederhold; Tejas Gandhi; Rainer Breitling; Dirk Jan Slotboom
Journal:  Mol Cell Proteomics       Date:  2011-07       Impact factor: 5.911

6.  Dissecting the unique nucleotide specificity of mimivirus nucleoside diphosphate kinase.

Authors:  Sandra Jeudy; Audrey Lartigue; Jean-Michel Claverie; Chantal Abergel
Journal:  J Virol       Date:  2009-05-13       Impact factor: 5.103

7.  A mitochondrial outer membrane-localized protein encoded by White spot syndrome virus.

Authors:  Muting Yan; Lihong Liu; Qianhui Liang; Jianhui He; Shaoping Weng; Jianguo He; Xiaopeng Xu
Journal:  Virus Genes       Date:  2016-01-27       Impact factor: 2.332

Review 8.  Revolutionizing membrane protein overexpression in bacteria.

Authors:  Susan Schlegel; Mirjam Klepsch; Dimitra Gialama; David Wickström; Dirk Jan Slotboom; Jan-Willem de Gier
Journal:  Microb Biotechnol       Date:  2009-09-04       Impact factor: 5.813

9.  Responses of the Housefly, Musca domestica, to the Hytrosavirus Replication: Impacts on Host's Vitellogenesis and Immunity.

Authors:  Henry M Kariithi; Xu Yao; Fahong Yu; Peter E Teal; Chelsea P Verhoeven; Drion G Boucias
Journal:  Front Microbiol       Date:  2017-04-05       Impact factor: 5.640

Review 10.  Viruses as modulators of mitochondrial functions.

Authors:  Sanjeev K Anand; Suresh K Tikoo
Journal:  Adv Virol       Date:  2013-10-24
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