OBJECTIVE: The aim of this study was to assess the quality of life and psychologic profile during radiation therapy for head and neck cancer. STUDY DESIGN AND SETTING: The University of Washington QoL instrument and the Hospital Anxiety and Depression Scale were administered to 202 patients at two or three time points during radiation therapy. RESULTS: A total of 118 (54.6%) patients completed the questionnaires at the beginning and at the end of the study. A mid-treatment dataset was also available for 67 (31.0%) patients. There was a statistically significant deterioration in composite QoL scores (P < 0.000) and a statistically significant increase in depression (P < 0.000). There was no difference in anxiety levels (P = 0.276). CONCLUSION: Patients undergoing radiation are increasingly depressed as treatment progresses, with worsening QoL during the treatment. SIGNIFICANCE: This study underlines the need for good psychologic support during radiation therapy in head and neck cancer.
OBJECTIVE: The aim of this study was to assess the quality of life and psychologic profile during radiation therapy for head and neck cancer. STUDY DESIGN AND SETTING: The University of Washington QoL instrument and the Hospital Anxiety and Depression Scale were administered to 202 patients at two or three time points during radiation therapy. RESULTS: A total of 118 (54.6%) patients completed the questionnaires at the beginning and at the end of the study. A mid-treatment dataset was also available for 67 (31.0%) patients. There was a statistically significant deterioration in composite QoL scores (P < 0.000) and a statistically significant increase in depression (P < 0.000). There was no difference in anxiety levels (P = 0.276). CONCLUSION:Patients undergoing radiation are increasingly depressed as treatment progresses, with worsening QoL during the treatment. SIGNIFICANCE: This study underlines the need for good psychologic support during radiation therapy in head and neck cancer.
Authors: J A Dean; L C Welsh; K H Wong; A Aleksic; E Dunne; M R Islam; A Patel; P Patel; I Petkar; I Phillips; J Sham; U Schick; K L Newbold; S A Bhide; K J Harrington; C M Nutting; S L Gulliford Journal: Clin Oncol (R Coll Radiol) Date: 2017-01-03 Impact factor: 4.126
Authors: Julia R Van Liew; Rebecca L Brock; Alan J Christensen; Lucy Hynds Karnell; Nitin A Pagedar; Gerry F Funk Journal: Head Neck Date: 2016-10-05 Impact factor: 3.147
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Authors: Christina Van Onselen; Laura B Dunn; Kathryn Lee; Marylin Dodd; Theresa Koetters; Claudia West; Steven M Paul; Bradley E Aouizerat; William Wara; Patrick Swift; Christine Miaskowski Journal: Eur J Oncol Nurs Date: 2010-01-18 Impact factor: 2.398
Authors: Amy Anne Donatelli-Lassig; Sonia A Duffy; Karen E Fowler; David L Ronis; Douglas B Chepeha; Jeffrey E Terrell Journal: Otolaryngol Head Neck Surg Date: 2008-10 Impact factor: 3.497
Authors: Jamie A Dean; Liam C Welsh; Dualta McQuaid; Kee H Wong; Aleksandar Aleksic; Emma Dunne; Mohammad R Islam; Anushka Patel; Priyanka Patel; Imran Petkar; Iain Phillips; Jackie Sham; Kate L Newbold; Shreerang A Bhide; Kevin J Harrington; Sarah L Gulliford; Christopher M Nutting Journal: Radiother Oncol Date: 2016-03-09 Impact factor: 6.280