| Literature DB >> 17208301 |
Lynda A O'Sullivan1, Clifford Liongue, Rowena S Lewis, Sarah E M Stephenson, Alister C Ward.
Abstract
The complexity of multicellular organisms is dependent on systems enabling cells to respond to specific stimuli. Cytokines and their receptors are one such system, whose perturbation can lead to a variety of disease states. This review represents an overview of our current understanding of the cytokine receptors, Janus kinases (Jaks), Signal transducers and activators of transcription (Stats) and Suppressors of cytokine signaling (Socs), focussing on their contribution to diseases of an immune or hematologic nature.Entities:
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Year: 2007 PMID： 17208301 DOI： 10.1016/j.molimm.2006.11.025
Source DB: PubMed Journal: Mol Immunol ISSN： 0161-5890 Impact factor: 4.407