Literature DB >> 17207632

Comorbidity in patients with cancer: prevalence and severity measured by cumulative illness rating scale.

Ulrich Wedding1, Bernd Roehrig, Almuth Klippstein, Peggy Steiner, Thomas Schaeffer, Ludger Pientka, Klaus Höffken.   

Abstract

Comorbidity is defined as the presence of one or more diseases in addition to an index disease. In elderly people, the number and severity of comorbidity increase with age. We report the comorbidity data of 536 patients treated as in-patients: 231 elderly cancer patients (ECP), 172 younger cancer patients (YCP) and 133 elderly patients admitted for non-cancer reasons (EMP). Comorbidity was assessed with the cumulative illness rating scale geriatric version (CIRS-G). Data on number of affected organ systems (levels 1-4), number of affected organ systems with severe disease (levels 3-4), and sum score of levels per patient are reported. The number of comorbidities increases with age. A 76% of ECP, 51% of YCP, and 79% of EMP have severe comorbidity. Palliative treatment approach is not associated with higher levels of comorbidity in ECP. Vascular disorders were the most common comorbidity. The difficulty to rate haematological comorbidity in cancer patients is reflected. This is the first report on detailed results of assessment of comorbidity measured by CIRS-G in cancer patients. In addition, we provide a comparison to an elderly group of patients admitted for non-cancer reasons.

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Year:  2007        PMID: 17207632     DOI: 10.1016/j.critrevonc.2006.11.001

Source DB:  PubMed          Journal:  Crit Rev Oncol Hematol        ISSN: 1040-8428            Impact factor:   6.312


  15 in total

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8.  Frail old patients as a target population for cancer trials.

Authors:  J-P Michel; S Pautex; M Aapro; G Zulian
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9.  The association of comorbidity measures and mortality in geriatric rehabilitation inpatients by cancer status: RESORT.

Authors:  Cheuk Huen Chan; Claire Maddison; Esmee M Reijnierse; Wen Kwang Lim; Andrea B Maier
Journal:  Support Care Cancer       Date:  2021-01-18       Impact factor: 3.359

10.  Radiation-induced toxicities and outcomes after radiotherapy are independent of patient age in elderly salivary gland cancer patients: results from a matched-pair analysis of a rare disease.

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Journal:  Eur Arch Otorhinolaryngol       Date:  2020-09-30       Impact factor: 2.503

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