Literature DB >> 17197496

Children's history of speech-language difficulties: genetic influences and associations with reading-related measures.

Laura Segebart DeThorne1, Sara A Hart, Stephen A Petrill, Kirby Deater-Deckard, Lee Anne Thompson, Chris Schatschneider, Megan Dunn Davison.   

Abstract

PURPOSE: This study examined (a) the extent of genetic and environmental influences on children's articulation and language difficulties and (b) the phenotypic associations between such difficulties and direct assessments of reading-related skills during early school-age years.
METHOD: Behavioral genetic analyses focused on parent-report data regarding the speech-language skills of 248 twin pairs (M = 6.08 years) from the Western Reserve Reading Project. In addition, phenotypic associations between children's speech-language status and direct assessments of early reading-related abilities were examined through hierarchical linear modeling (HLM).
RESULTS: Probandwise concordance rates and intraclass tetrachoric correlations indicated high heritability for children's difficulties in expressive language and articulation, with estimates of .54 and .97 accordingly. HLM results indicated that children with histories of speech-language difficulties scored significantly lower than unaffected children on various measures of early reading-related abilities.
CONCLUSIONS: Results from the parent-report survey provided converging evidence of genetic effects on children's speech and language difficulties and suggest that children with a history of speech-language difficulties are at risk for lower performance on early reading-related measures. The extent of risk differed across measures and appeared greatest for children who demonstrated a history of difficulties across articulation, expressive language, and receptive language. Implications for future genetic research and clinical practice are discussed.

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Mesh:

Year:  2006        PMID: 17197496      PMCID: PMC2659564          DOI: 10.1044/1092-4388(2006/092)

Source DB:  PubMed          Journal:  J Speech Lang Hear Res        ISSN: 1092-4388            Impact factor:   2.297


  39 in total

1.  Prevalence of speech delay in 6-year-old children and comorbidity with language impairment.

Authors:  L D Shriberg; J B Tomblin; J L McSweeny
Journal:  J Speech Lang Hear Res       Date:  1999-12       Impact factor: 2.297

2.  Low expressive vocabulary: higher heritability as a function of more severe cases.

Authors:  Laura S DeThorne; Stephen A Petrill; Marianna E Hayiou-Thomas; Robert Plomin
Journal:  J Speech Lang Hear Res       Date:  2005-08       Impact factor: 2.297

3.  Family histories of children with SLI who show extended optional infinitives.

Authors:  M L Rice; K R Haney; K Wexler
Journal:  J Speech Lang Hear Res       Date:  1998-04       Impact factor: 2.297

4.  Logistic regression analysis of twin data: estimation of parameters of the multifactorial liability-threshold model.

Authors:  P C Sham; E E Walters; M C Neale; A C Heath; C J MacLean; K S Kendler
Journal:  Behav Genet       Date:  1994-05       Impact factor: 2.805

Review 5.  Developmental dyslexia and specific language impairment: same or different?

Authors:  Dorothy V M Bishop; Margaret J Snowling
Journal:  Psychol Bull       Date:  2004-11       Impact factor: 17.737

6.  Genetic influences on language impairment and literacy problems in children: same or different?

Authors:  D V Bishop
Journal:  J Child Psychol Psychiatry       Date:  2001-02       Impact factor: 8.982

Review 7.  Generalist genes and learning disabilities.

Authors:  Robert Plomin; Yulia Kovas
Journal:  Psychol Bull       Date:  2005-07       Impact factor: 17.737

8.  Hidden language impairments in children: parallels between poor reading comprehension and specific language impairment?

Authors:  Kate Nation; Paula Clarke; Catherine M Marshall; Marianne Durand
Journal:  J Speech Lang Hear Res       Date:  2004-02       Impact factor: 2.297

9.  Are specific language impairment and dyslexia distinct disorders?

Authors:  Hugh W Catts; Suzanne M Adlof; Tiffany P Hogan; Susan Ellis Weismer
Journal:  J Speech Lang Hear Res       Date:  2005-12       Impact factor: 2.297

10.  Genetic and environmental influence on language impairment in 4-year-old same-sex and opposite-sex twins.

Authors:  Essi Viding; Frank M Spinath; Thomas S Price; Dorothy V M Bishop; Philip S Dale; Robert Plomin
Journal:  J Child Psychol Psychiatry       Date:  2004-02       Impact factor: 8.982

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  18 in total

1.  Literacy outcomes of children with early childhood speech sound disorders: impact of endophenotypes.

Authors:  Barbara A Lewis; Allison A Avrich; Lisa A Freebairn; Amy J Hansen; Lara E Sucheston; Iris Kuo; H Gerry Taylor; Sudha K Iyengar; Catherine M Stein
Journal:  J Speech Lang Hear Res       Date:  2011-09-19       Impact factor: 2.297

Review 2.  Genetic and environmental influences on early speech, language and literacy development.

Authors:  Marianna E Hayiou-Thomas
Journal:  J Commun Disord       Date:  2008-03-25       Impact factor: 2.288

3.  Genetic effects on children's conversational language use.

Authors:  Laura S DeThorne; Stephen A Petrill; Sara A Hart; Ron W Channell; Rebecca J Campbell; Kirby Deater-Deckard; Lee Anne Thompson; David J Vandenbergh
Journal:  J Speech Lang Hear Res       Date:  2008-04       Impact factor: 2.297

4.  Heritability of Specific Language Impairment and Nonspecific Language Impairment at Ages 4 and 6 Years Across Phenotypes of Speech, Language, and Nonverbal Cognition.

Authors:  Mabel L Rice; Catherine L Taylor; Stephen R Zubrick; Lesa Hoffman; Kathleen K Earnest
Journal:  J Speech Lang Hear Res       Date:  2020-03-12       Impact factor: 2.297

5.  Association between AVPR1A, DRD2, and ASPM and endophenotypes of communication disorders.

Authors:  Catherine M Stein; Barbara Truitt; Fenghua Deng; Allison Avrich Ciesla; Feiyou Qiu; Peronne Joseph; Rekha Raghavendra; Jeremy Fondran; Robert P Igo; Jessica Tag; Lisa Freebairn; H Gerry Taylor; Barbara A Lewis; Sudha K Iyengar
Journal:  Psychiatr Genet       Date:  2014-10       Impact factor: 2.458

6.  Conversational language use as a predictor of early reading development: language history as a moderating variable.

Authors:  Laura Segebart DeThorne; Stephen A Petrill; Chris Schatschneider; Laurie Cutting
Journal:  J Speech Lang Hear Res       Date:  2010-02       Impact factor: 2.297

7.  Volubility as a mediator in the associations between conversational language measures and child temperament.

Authors:  Laura Segebart DeThorne; Kirby Deater-Deckard; Jamie Mahurin-Smith; Mary-Kelsey Coletto; Stephen A Petrill
Journal:  Int J Lang Commun Disord       Date:  2011-04-13       Impact factor: 3.020

8.  Genetic and Environmental Links Between Natural Language Use and Cognitive Ability in Toddlers.

Authors:  Caitlin F Canfield; Lisa R Edelson; Kimberly J Saudino
Journal:  Child Dev       Date:  2016-08-30

9.  Convergent genetic linkage and associations to language, speech and reading measures in families of probands with Specific Language Impairment.

Authors:  Mabel L Rice; Shelley D Smith; Javier Gayán
Journal:  J Neurodev Disord       Date:  2009-08-26       Impact factor: 4.025

Review 10.  Speaking genes or genes for speaking? Deciphering the genetics of speech and language.

Authors:  Elena L Grigorenko
Journal:  J Child Psychol Psychiatry       Date:  2009-01       Impact factor: 8.982

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