Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Evaluation of the in vivo activity of tribendimidine against Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis, and Opisthorchis viverrini.

Literature DB >> 17194822

Evaluation of the in vivo activity of tribendimidine against Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis, and Opisthorchis viverrini.

Jennifer Keiser¹, Xiao Shu-Hua, Jacques Chollet, Marcel Tanner, Jürg Utzinger.

Abstract

We examined the in vivo activity of tribendimidine against selected trematodes. A single 150-mg/kg dose of tribendimidine achieved a 99.1% reduction of Clonorchis sinensis in rats. A 400-mg/kg dose of tribendimidine reduced Opisthorchis viverrini in hamsters by 95.7%. High doses of tribendimidine showed no activity against Schistosoma mansoni and Fasciola hepatica.

Entities: Chemical Species

Mesh：

Substances：

Year: 2006 PMID： 17194822 PMCID： PMC1803157 DOI： 10.1128/AAC.01366-06

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

15 in total

1. Little effect of praziquantel or artemisinin on clonorchiasis in Northern Vietnam. A pilot study.

Authors: N Tinga; N De; H V Vien; L Chau; N D Toan; P A Kager; P J Vries
Journal: Trop Med Int Health Date: 1999-12 Impact factor: 2.622

Review 2. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk.

Authors: Peter Steinmann; Jennifer Keiser; Robert Bos; Marcel Tanner; Jürg Utzinger
Journal: Lancet Infect Dis Date: 2006-07 Impact factor: 25.071

3. [Experimental therapeutic efficacy of a new anti-hookworm drug, tribendimidin].

Authors: H N Ren; B Z Cheng; Z N Zhuang
Journal: Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi Date: 1987

Review 4. Tribendimidine: a promising, safe and broad-spectrum anthelmintic agent from China.

Authors: Shu-Hua Xiao; Wu Hui-Ming; Marcel Tanner; Jürg Utzinger; Wang Chong
Journal: Acta Trop Date: 2005-04 Impact factor: 3.112

5. Control of foodborne trematode infections. Report of a WHO Study Group.

Authors:
Journal: World Health Organ Tech Rep Ser Date: 1995

6. A small-scale survey of intestinal helminthic infections among the residents near Pakse, Laos.

Authors: J Y Chai; B Hongvanthong
Journal: Korean J Parasitol Date: 1998-03 Impact factor: 1.341

7. Social and behavioral factors associated with Clonorchis infection in one commune located in the Red River Delta of Vietnam.

Authors: P Nontasut; T V Thong; J Waikagul; M T Anantaphruti; W Fungladda; N Imamee; N V De
Journal: Southeast Asian J Trop Med Public Health Date: 2003-06 Impact factor: 0.267

Review 8. Chemotherapy for major food-borne trematodes: a review.

Authors: Jennifer Keiser; Jürg Utzinger
Journal: Expert Opin Pharmacother Date: 2004-08 Impact factor: 3.889

9. [Intestinal parasite and Clonorchis sinensis infection among the inhabitants in the upper stream of Taechong Dam, Kumgang (River)].

Authors: C H Kim; Y E Na; N M Kim; D W Shin; D Y Chang
Journal: Korean J Parasitol Date: 1994-12 Impact factor: 1.341

Review 10. Emerging foodborne trematodiasis.

Authors: Jennifer Keiser; Jürg Utzinger
Journal: Emerg Infect Dis Date: 2005-10 Impact factor: 6.883

18 in total

1. Effectiveness of mefloquine against Clonorchis sinensis in rats and Paragonimus westermani in dogs.

Authors: Shu-hua Xiao; Jian Xue; Xu Li-li; Yong-nian Zhang; Hui-qing Qiang
Journal: Parasitol Res Date: 2010-08-03 Impact factor: 2.289

2. Comparative effect of mebendazole, albendazole, tribendimidine, and praziquantel in treatment of rats infected with Clonorchis sinensis.

Authors: Shu-hua Xiao; Jian Xue; Li-li Xu; Yong-nian Zhang; Hui-qin Qiang
Journal: Parasitol Res Date: 2010-12-07 Impact factor: 2.289

3. The effect of tribendimidine and its metabolites against Necator americanus in golden hamsters and Nippostrongylus braziliensis in rats.

Authors: Jian Xue; Shu-hua Xiao; Li-li Xu; Hui-qing Qiang
Journal: Parasitol Res Date: 2010-02-13 Impact factor: 2.289

10. Combination chemotherapy against Clonorchis sinensis: experiments with artemether, artesunate, OZ78, praziquantel, and tribendimidine in a rat model.

Authors: Jennifer Keiser; Shu-Hua Xiao; Thomas A Smith; Jürg Utzinger
Journal: Antimicrob Agents Chemother Date: 2009-07-06 Impact factor: 5.191