Literature DB >> 17188802

The stepping motor protein as a feedback control ratchet.

Martin Bier1.   

Abstract

It is explained how going from a one headed motor protein to a stepping two headed motor protein is equivalent to going from a stochastically flashing ratchet to a feedback control ratchet. Both these ratchets have been well studied in the literature and their speeds and efficiencies are briefly reviewed. Next it is shown how a feedback control ratchet mechanism model can account for very accurate recent data obtained on kinesin. Finally, the role of internal friction in the operation of stepping motor proteins is discussed.

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Year:  2006        PMID： 17188802     DOI： 10.1016/j.biosystems.2006.07.013

Source DB:  PubMed          Journal:  Biosystems        ISSN： 0303-2647            Impact factor:   1.973


  2 in total

Review 1.  Synthetic biology approaches to dissecting linear motor protein function: towards the design and synthesis of artificial autonomous protein walkers.

Authors:  Heiner Linke; Birte Höcker; Ken'ya Furuta; Nancy R Forde; Paul M G Curmi
Journal:  Biophys Rev       Date:  2020-07-10

2.  Mechano-chemical kinetics of DNA replication: identification of the translocation step of a replicative DNA polymerase.

Authors:  José A Morin; Francisco J Cao; José M Lázaro; J Ricardo Arias-Gonzalez; José M Valpuesta; José L Carrascosa; Margarita Salas; Borja Ibarra
Journal:  Nucleic Acids Res       Date:  2015-03-23       Impact factor: 16.971
  2 in total

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