Literature DB >> 17188682

Fibroblast growth factor-10 prevents H2O2-induced cell cycle arrest by regulation of G1 cyclins and cyclin dependent kinases.

D Upadhyay1, W Chang, K Wei, M Gao, G D Rosen.   

Abstract

We studied the effects of fibroblast growth factor (FGF-10) on H2O2-induced alveolar epithelial cell (AEC) G1 arrest and the role of G1 cyclins. FGF-10 prevented H2O2-induced AEC G1 arrest. FGF-10 induced 2-4-fold increase in cyclin E, cyclin A and CDKs (2,4) alone and in AEC treated with H2O2. H2O2 downregulated cyclin D1; FGF-10 blocked these effects. FGF-10 prevented H2O2-induced upregulation of CDK inhibitor, p21. SiRNAp21 blocked H2O2-induced downregulation of cyclins, CDKs and AEC G1 arrest. Accordingly, we provide first evidence that FGF-10 regulates G1 cyclins and CDKs, and prevents H2O2-induced AEC G1 arrest.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17188682      PMCID： PMC1861821          DOI： 10.1016/j.febslet.2006.12.020

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  21 in total

Review 1.  CDK inhibitors: positive and negative regulators of G1-phase progression.

Authors:  C J Sherr; J M Roberts
Journal:  Genes Dev       Date:  1999-06-15       Impact factor: 11.361

Review 2.  Regulation of G1 phase progression by growth factors and the extracellular matrix.

Authors:  E Hulleman; J Boonstra
Journal:  Cell Mol Life Sci       Date:  2001-01       Impact factor: 9.261

Review 3.  Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle.

Authors:  S V Ekholm; S I Reed
Journal:  Curr Opin Cell Biol       Date:  2000-12       Impact factor: 8.382

4.  Fibroblast growth factor-10 prevents asbestos-induced alveolar epithelial cell apoptosis by a mitogen-activated protein kinase-dependent mechanism.

Authors:  Daya Upadhyay; Vijayalakshmi Panduri; David W Kamp
Journal:  Am J Respir Cell Mol Biol       Date:  2004-12-23       Impact factor: 6.914

5.  H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression.

Authors:  Karin Barnouin; Marlène L Dubuisson; Emma S Child; Silvia Fernandez de Mattos; Janet Glassford; René H Medema; David J Mann; Eric W-F Lam
Journal:  J Biol Chem       Date:  2002-02-04       Impact factor: 5.157

6.  Inhibition of cell proliferation by the PCNA-binding region of p21 expressed as a GFP miniprotein.

Authors:  H Mattock; D P Lane; E Warbrick
Journal:  Exp Cell Res       Date:  2001-05-01       Impact factor: 3.905

7.  Fibroblast growth factor and insulin-like growth factor differentially modulate the apoptosis and G1 arrest induced by anti-epidermal growth factor receptor monoclonal antibody.

Authors:  B Liu; M Fang; Y Lu; J Mendelsohn; Z Fan
Journal:  Oncogene       Date:  2001-04-05       Impact factor: 9.867

Review 8.  Role of cyclins in epithelial response to oxidants.

Authors:  A Clement; A Henrion-Caude; V Besnard; S Corroyer
Journal:  Am J Respir Crit Care Med       Date:  2001-11-15       Impact factor: 21.405

Review 9.  Pathways governing G1/S transition and their response to DNA damage.

Authors:  J Bartek; J Lukas
Journal:  FEBS Lett       Date:  2001-02-16       Impact factor: 4.124

10.  Proliferation of intimal smooth muscle cells. Attenuation of basic fibroblast growth factor 2-stimulated proliferation is associated with increased expression of cell cycle inhibitors.

Authors:  N E Olson; J Kozlowski; M A Reidy
Journal:  J Biol Chem       Date:  2000-04-14       Impact factor: 5.157
View more
  7 in total

1.  Growth arrest of lung carcinoma cells (A549) by polyacrylate-anchored peroxovanadate by activating Rac1-NADPH oxidase signalling axis.

Authors:  Nirupama Chatterjee; Tarique Anwar; Nashreen S Islam; T Ramasarma; Gayatri Ramakrishna
Journal:  Mol Cell Biochem       Date:  2016-07-19       Impact factor: 3.396

2.  Cell damaging by irradiating non-thermal plasma to the water: Mathematical modeling of chemical processes.

Authors:  Leila Karami-Gadallo; Leila Ataie-Fashtami; Mahmood Ghoranneviss; Majid Pouladian; Dariush Sardari
Journal:  Mol Biol Res Commun       Date:  2018-09

3.  Effect of EGF and FGF on the expansion properties of human umbilical cord mesenchymal cells.

Authors:  Parvin Salehinejad; Noorjahan Banu Alitheen; Ali Mandegary; Seyed Noureddin Nematollahi-Mahani; Ehsan Janzamin
Journal:  In Vitro Cell Dev Biol Anim       Date:  2013-05-25       Impact factor: 2.416

4.  Ambient particulate matter induces alveolar epithelial cell cycle arrest: role of G1 cyclins.

Authors:  Jingmei Zhang; Andrew J Ghio; Mingxing Gao; Ke Wei; Glenn D Rosen; Daya Upadhyay
Journal:  FEBS Lett       Date:  2007-10-23       Impact factor: 4.124

5.  Proteomics and phosphoproteomics study of LCMT1 overexpression and oxidative stress: overexpression of LCMT1 arrests H2O2-induced lose of cells viability.

Authors:  Xinhang Wang; Shen Tang; Fu Qin; Yuyang Liu; Ziwei Liang; Haiqing Cai; Laiming Mo; Deqiang Xiao; Songcao Guo; Yiqiang Ouyang; Bin Sun; Cailing Lu; Xiyi Li
Journal:  Redox Rep       Date:  2019-12       Impact factor: 4.412

Review 6.  Molecular and Cellular Effects of Hydrogen Peroxide on Human Lung Cancer Cells: Potential Therapeutic Implications.

Authors:  Gabriela Vilema-Enríquez; Aurora Arroyo; Marcelo Grijalva; Ricardo Israel Amador-Zafra; Javier Camacho
Journal:  Oxid Med Cell Longev       Date:  2016-06-08       Impact factor: 6.543

7.  Expression and purification of human keratinocyte growth factor 2 by fusion with SUMO.

Authors:  Xiaoping Wu; Changjun Nie; Zhifeng Huang; Yanfang Nie; Qiuxia Yan; Yecheng Xiao; Zhijian Su; Yadong Huang; Jian Xiao; Yaoying Zeng; Yi Tan; Wenke Feng; Xiaokun Li
Journal:  Mol Biotechnol       Date:  2008-12-18       Impact factor: 2.695
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.