Literature DB >> 17185992

The PharmGKB: integration, aggregation, and annotation of pharmacogenomic data and knowledge.

A E Hodge1, R B Altman, T E Klein.   

Abstract

The Pharmacogenetics and Pharmacogenomics Knowledge Base, PharmGKB (http://www.pharmgkb.org), curates pharmacogenetic and pharmacogenomic information to generate knowledge concerning the relationships among genes, drugs, and diseases, and the effects of gene variation on these relationships. PharmGKB curators collect information on genotype-phenotype relationships both from the literature and from the deposition of primary research data into our database. Their goal is to catalyze pharmacogenetic and pharmacogenomic research.

Mesh:

Year:  2007        PMID: 17185992     DOI: 10.1038/sj.clpt.6100048

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


  6 in total

1.  PharmGKB: understanding the effects of individual genetic variants.

Authors:  Katrin Sangkuhl; Dorit S Berlin; Russ B Altman; Teri E Klein
Journal:  Drug Metab Rev       Date:  2008       Impact factor: 4.518

2.  PharmGKB: an integrated resource of pharmacogenomic data and knowledge.

Authors:  Li Gong; Ryan P Owen; Winston Gor; Russ B Altman; Teri E Klein
Journal:  Curr Protoc Bioinformatics       Date:  2008-09

3.  Feasibility of incorporating genomic knowledge into electronic medical records for pharmacogenomic clinical decision support.

Authors:  Casey Lynnette Overby; Peter Tarczy-Hornoch; James I Hoath; Ira J Kalet; David L Veenstra
Journal:  BMC Bioinformatics       Date:  2010-10-28       Impact factor: 3.169

4.  DDPC: Dragon Database of Genes associated with Prostate Cancer.

Authors:  Monique Maqungo; Mandeep Kaur; Samuel K Kwofie; Aleksandar Radovanovic; Ulf Schaefer; Sebastian Schmeier; Ekow Oppon; Alan Christoffels; Vladimir B Bajic
Journal:  Nucleic Acids Res       Date:  2010-09-29       Impact factor: 16.971

5.  TARGETgene: a tool for identification of potential therapeutic targets in cancer.

Authors:  Chia-Chin Wu; David D'Argenio; Shahab Asgharzadeh; Timothy Triche
Journal:  PLoS One       Date:  2012-08-31       Impact factor: 3.240

6.  DrugBank: a knowledgebase for drugs, drug actions and drug targets.

Authors:  David S Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali
Journal:  Nucleic Acids Res       Date:  2007-11-29       Impact factor: 16.971

  6 in total

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