Literature DB >> 1718520

Ketamine potentiates 5-HT3 receptor-mediated currents in rabbit nodose ganglion neurones.

J A Peters1, H M Malone, J J Lambert.   

Abstract

The interaction of ketamine with the 5-HT3 receptor of rabbit nodose ganglion neurones is described. Ketamine (3-30 microM) enhanced 5-HT3 receptor-mediated currents recorded under voltage-clamp conditions. This action did not appear to be related to the known effect of ketamine of inhibiting 5-HT uptake.

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Year:  1991        PMID： 1718520      PMCID： PMC1907797          DOI： 10.1111/j.1476-5381.1991.tb09837.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  5 in total

1.  Na+ and Ca2+ currents of acutely isolated adult rat nodose ganglion cells.

Authors:  S R Ikeda; G G Schofield; F F Weight
Journal:  J Neurophysiol       Date:  1986-03       Impact factor: 2.714

2.  Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine.

Authors:  J F MacDonald; Z Miljkovic; P Pennefather
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3.  The mechanism and site of action of ketamine on skeletal muscle.

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4.  Inhibition of neuronal 5-HT uptake by ketamine, but not halothane, involves disruption of substrate recognition by the transporter.

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5.  Examination of the relationship between the uptake site for 5-hydroxytryptamine and the high affinity binding site for [3H]imipramine. II. The role of sodium ions.

Authors:  M D Wood
Journal:  Neuropharmacology       Date:  1987-08       Impact factor: 5.250
  5 in total
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Journal:  J Physiol       Date:  1999-09-15       Impact factor: 5.182

Review 2.  Allosteric modulation of the 5-HT(3) receptor.

Authors:  Paul A Davies
Journal:  Curr Opin Pharmacol       Date:  2011-02-20       Impact factor: 5.547

3.  The interaction of trichloroethanol with murine recombinant 5-HT3 receptors.

Authors:  D L Downie; A G Hope; D Belelli; J J Lambert; J A Peters; K R Bentley; L J Steward; C Y Chen; N M Barnes
Journal:  Br J Pharmacol       Date:  1995-04       Impact factor: 8.739

4.  Actions of general anaesthetics on 5-HT3 receptors in N1E-115 neuroblastoma cells.

Authors:  A Jenkins; N P Franks; W R Lieb
Journal:  Br J Pharmacol       Date:  1996-04       Impact factor: 8.739

5.  In vivo measurement of protein functional changes.

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  5 in total

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