| Literature DB >> 17178222 |
Rosa Arienzo1, Sue Cramp, Hazel J Dyke, Peter M Lockey, Dennis Norman, Alan G Roach, Phil Smith, Melanie Wong, Stephen P Wren.
Abstract
We have modified the previously reported 2-aminoquinoline 1 to provide two novel series of MCH-1R antagonists. Representative compounds from the quinazoline and benzimidazole series have been shown to be potent and selective, with promising in vitro eADME profiles.Entities:
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Year: 2006 PMID： 17178222 DOI： 10.1016/j.bmcl.2006.11.092
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823