Literature DB >> 17176015

Thoracic myelopathy caused by ossification of the ligamentum flavum: clinical features and surgical results in the Japanese population.

Toshimi Aizawa1, Tetsuro Sato, Hirotoshi Sasaki, Takashi Kusakabe, Naoki Morozumi, Shoichi Kokubun.   

Abstract

OBJECT: Data obtained in patients with thoracic myelopathy caused by ossification of the ligamentum flavum (OLF) were retrospectively reviewed to clarify clinical features and surgical outcomes in the Japanese population.
METHODS: Seventy-two patients who underwent surgery for OLF-induced myelopathy in the Miyagi Prefecture, Japan, between 1988 and 2002 were observed for at least 2 years. Clinical data were collected from medical and operative records. The patients were evaluated pre- and postoperatively using the modified Japanese Orthopaedic Association (JOA) scale (maximum score 11). The relationships among various factors (age, sex, and preoperative duration of symptoms) affecting the preoperative severity of myelopathy and postoperative improvement were also examined.
CONCLUSIONS: In this series the surgical outcome was relatively good and depended on the severity of myelopathy; thus early and correct diagnosis is required to avoid poorer results. The male/female ratio was 3:2 and the mean patient age at surgery was 61 years for men and 68 for women. The patients commonly noticed numbness or pain in their lower legs or gait disturbances. In a total of 104 decompressed intervertebral disc levels, more than 80% of the ossified ligaments were at the T9-10 level or lower. The mean preoperative JOA score of 5.1 improved to 7.9 after an average of 46 months. The postoperative results statistically depended on the preoperative severity of myelopathy. Among studies of patients with OLF-related myelopathy, the present study had the largest sample size, which should help clarify the clinical features of OLF myelopathy.

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Year:  2006        PMID: 17176015     DOI: 10.3171/spi.2006.5.6.514

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  50 in total

1.  Kinematic evaluation of thoracic spinal cord sagittal diameter and the space available for cord using weight-bearing kinematic magnetic resonance imaging.

Authors:  Permsak Paholpak; Aidin Abedi; Rattanaporn Chamnan; Kunlavit Chantarasirirat; Koji Tamai; Zorica Buser; Jeffrey C Wang
Journal:  Spinal Cord       Date:  2018-09-24       Impact factor: 2.772

2.  Multiple-level ossification of the ligamentum flavum in the cervical spine combined with calcification of the cervical ligamentum flavum and posterior atlanto-axial membrane.

Authors:  Hirokazu Inoue; Atsushi Seichi; Atsushi Kimura; Teruaki Endo; Yuichi Hoshino
Journal:  Eur Spine J       Date:  2012-10-06       Impact factor: 3.134

3.  Aggravation of spinal cord compromise following new osteoporotic vertebral compression fracture prevented by teriparatide in patients with surgical contraindications.

Authors:  Y Zhao; R Xue; N Shi; Y Xue; Y Zong; W Lin; B Pei; C Sun; R Fan; Y Jiang
Journal:  Osteoporos Int       Date:  2016-05-31       Impact factor: 4.507

4.  Clinically significant radiographic parameter for thoracic myelopathy caused by ossification of the ligamentum flavum.

Authors:  Byung-Jou Lee; Jin Hoon Park; Sang-Ryong Jeon; Seung-Chul Rhim; Sung Woo Roh
Journal:  Eur Spine J       Date:  2018-09-06       Impact factor: 3.134

5.  Reoperation rates after fenestration for lumbar spinal canal stenosis: a 20-year period survival function method analysis.

Authors:  Toshimi Aizawa; Hiroshi Ozawa; Takashi Kusakabe; Yasuhisa Tanaka; Akira Sekiguchi; Ko Hashimoto; Haruo Kanno; Naoki Morozumi; Yushin Ishii; Tetsuro Sato; Eiji Takahashi; Shoichi Kokubun; Eiji Itoi
Journal:  Eur Spine J       Date:  2014-07-30       Impact factor: 3.134

6.  The CT and intraoperative observation of pedicel-ossification tunnel in 151 cases of thoracic spinal stenosis from ossification of ligamentum flavum.

Authors:  Ying Zhao; Yuan Xue; Nianke Shi; Yaqi Zong; Zhong Yang; Dong He; Yi Wang; Huairong Ding; Zhiyang Li; Yanming Tang
Journal:  Eur Spine J       Date:  2014-03-08       Impact factor: 3.134

7.  A diagnostic study of thoracic myelopathy due to ossification of ligamentum flavum.

Authors:  Fabo Feng; Chuiguo Sun; ZhongQiang Chen
Journal:  Eur Spine J       Date:  2015-03-06       Impact factor: 3.134

Review 8.  Recurrence of ossification of ligamentum flavum at the same intervertebral level in the thoracic spine: a report of two cases and review of the literature.

Authors:  Haruo Kanno; Tadahisa Takahashi; Toshimi Aizawa; Ko Hashimoto; Eiji Itoi; Hiroshi Ozawa
Journal:  Eur Spine J       Date:  2017-08-24       Impact factor: 3.134

9.  Phenotypic characterization of ligamentum flavum cells from patients with ossification of ligamentum flavum.

Authors:  Zhao-Ming Zhong; Jian-Ting Chen
Journal:  Yonsei Med J       Date:  2009-06-23       Impact factor: 2.759

10.  Severe facet joint arthrosis caused c7/t1 myelopathy: a case report.

Authors:  Toshimi Aizawa; Hiroshi Ozawa; Takeshi Hoshikawa; Takashi Kusakabe; Eiji Itoi
Journal:  Case Rep Med       Date:  2009-06-16
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