Literature DB >> 17169593

Methylphenidate improves reading performance in children with attention deficit hyperactivity disorder and comorbid dyslexia: an unblinded clinical trial.

Esther H H Keulers1, Jos G M Hendriksen, Frans J M Feron, Renske Wassenberg, Mea G F Wuisman-Frerker, Jelle Jolles, Johan S H Vles.   

Abstract

Attention Deficit Hyperactivity Disorder (ADHD) and dyslexia are frequently co-occurring disorders. Although methylphenidate (MPH) is the primary treatment for ADHD, the effect on reading in children with these comorbid problems is not yet known. This study was an unblinded clinical trial to evaluate the reading performance before and after treatment with MPH. Reading performance was compared with General Linear Model repeated measures between three groups: (1) an experimental group of children with both ADHD and dyslexia (N = 24), (2) a control group of children with ADHD (N = 9) and (3) a control group of children with dyslexia (N = 10). MPH improved reading performance significantly stronger in the experimental group than in the control groups; the number of correctly read words increased to a larger extent. In conclusion, MPH proved to be an aid in the reading process of children with ADHD and comorbid dyslexia by improving the learning conditions, but MPH cannot cure the reading disorder. Future research should study the effect of MPH on reading in a double-blind clinical trial.

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Year:  2006        PMID: 17169593     DOI: 10.1016/j.ejpn.2006.10.002

Source DB:  PubMed          Journal:  Eur J Paediatr Neurol        ISSN: 1090-3798            Impact factor:   3.140


  12 in total

1.  Using ADHD Medications to Treat Coexisting ADHD and Reading Disorders: A Systematic Review.

Authors:  Tanya E Froehlich; Jason Fogler; William J Barbaresi; Nada A Elsayed; Steven W Evans; Eugenia Chan
Journal:  Clin Pharmacol Ther       Date:  2018-08-30       Impact factor: 6.875

2.  Comparing treatments for children with ADHD and word reading difficulties: A randomized clinical trial.

Authors:  Leanne Tamm; Carolyn A Denton; Jeffery N Epstein; Christopher Schatschneider; Heather Taylor; L Eugene Arnold; Oscar Bukstein; Julia Anixt; Anson Koshy; Nicholas C Newman; Jan Maltinsky; Patricia Brinson; Richard E A Loren; Mary R Prasad; Linda Ewing-Cobbs; Aaron Vaughn
Journal:  J Consult Clin Psychol       Date:  2017-03-23

3.  A randomized, double-blind, cross-over, phase IV trial of oros-methylphenidate (CONCERTA(®)) and generic novo-methylphenidate ER-C (NOVO-generic).

Authors:  Angelo Fallu; Farida Dabouz; Melissa Furtado; Leena Anand; Martin A Katzman
Journal:  Ther Adv Psychopharmacol       Date:  2016-05-01

4.  The genetic association between ADHD symptoms and reading difficulties: the role of inattentiveness and IQ.

Authors:  Yannis Paloyelis; Fruhling Rijsdijk; Alexis C Wood; Philip Asherson; Jonna Kuntsi
Journal:  J Abnorm Child Psychol       Date:  2010-11

5.  The Effects of ADHD Treatment and Reading Intervention on the Fluency and Comprehension of Children with ADHD and Word Reading Difficulties: A Randomized Clinical Trial.

Authors:  Carolyn A Denton; Leanne Tamm; Christopher Schatschneider; Jeffery N Epstein
Journal:  Sci Stud Read       Date:  2019-07-19

6.  The Impact of Intensive Reading Intervention on Level of Attention in Middle School Students.

Authors:  Greg Roberts; Shruti Rane; Anna-Mária Fall; Carolyn A Denton; Jack M Fletcher; Sharon Vaughn
Journal:  J Clin Child Adolesc Psychol       Date:  2014-06-02

7.  Atomoxetine for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children with ADHD and dyslexia.

Authors:  Calvin R Sumner; Susan Gathercole; Michael Greenbaum; Richard Rubin; David Williams; Millie Hollandbeck; Linda Wietecha
Journal:  Child Adolesc Psychiatry Ment Health       Date:  2009-12-15       Impact factor: 3.033

Review 8.  Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of adverse events in non-randomised studies.

Authors:  Ole Jakob Storebø; Nadia Pedersen; Erica Ramstad; Maja Lærke Kielsholm; Signe Sofie Nielsen; Helle B Krogh; Carlos R Moreira-Maia; Frederik L Magnusson; Mathilde Holmskov; Trine Gerner; Maria Skoog; Susanne Rosendal; Camilla Groth; Donna Gillies; Kirsten Buch Rasmussen; Dorothy Gauci; Morris Zwi; Richard Kirubakaran; Sasja J Håkonsen; Lise Aagaard; Erik Simonsen; Christian Gluud
Journal:  Cochrane Database Syst Rev       Date:  2018-05-09

Review 9.  Children with Attention Deficit/Hyperactivity Disorder and Reading Disability: A Review of the Efficacy of Medication Treatments.

Authors:  Christina Gray; Emma A Climie
Journal:  Front Psychol       Date:  2016-07-05

10.  Study of the effect of Memantine therapy on the treatment of dyslexia in children.

Authors:  Mojgan Karahmadi; Marzieh Salehi; Maryam Rezayi; Behzad Mahaki
Journal:  J Res Med Sci       Date:  2017-12-26       Impact factor: 1.852

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