| Literature DB >> 17164669 |
Zhi-Hong Chi1, Xin Wang, Zhan-You Wang, Hui-Ling Gao, Annica Dahlstrom, Liping Huang.
Abstract
The cellular localization of zinc transporter 7 protein in the mouse choroid plexus was examined in this study. Zinc transporter 7 immunoreactive cells were detected in the third, lateral, and fourth ventricles of CD-1 mouse brain. Distinct zinc transporter 7 immunoreactivity was concentrated in the perinuclear regions of the positive cells. The results from zinc autometallography showed that zinc-positive grains were also predominantly located in the perinuclear areas. Ultrastructural localization showed that zinc transporter 7 immunostaining was predominantly present in the membrane and cisternae of the cis-Golgi networks and some vesicle compartments. The results support the notion that zinc transporter 7 may participate in the transport of the cytoplasmic zinc into the Golgi apparatus, and may be involved in local packaging of zinc-binding proteins in the mouse choroid plexus.Entities:
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Year: 2006 PMID： 17164669 DOI： 10.1097/01.wnr.0000239968.06438.c5
Source DB: PubMed Journal: Neuroreport ISSN： 0959-4965 Impact factor: 1.837