Literature DB >> 17156062

Sunshine is good medicine. The health benefits of ultraviolet-B induced vitamin D production.

W B Grant1, R C Strange, C F Garland.   

Abstract

Most public health statements regarding exposure to solar ultraviolet radiation (UVR) recommend avoiding it, especially at midday, and using sunscreen. Excess UVR is a primary risk factor for skin cancers, premature photoageing and the development of cataracts. In addition, some people are especially sensitive to UVR, sometimes due to concomitant illness or drug therapy. However, if applied uncritically, these guidelines may actually cause more harm than good. Humans derive most of their serum 25-hydroxycholecalciferol (25(OH)D3) from solar UVB radiation (280-315 nm). Serum 25(OH)D3 metabolite levels are often inadequate for optimal health in many populations, especially those with darker skin pigmentation, those living at high latitudes, those living largely indoors and in urban areas, and during winter in all but the sunniest climates. In the absence of adequate solar UVB exposure or artificial UVB, vitamin D can be obtained from dietary sources or supplements. There is compelling evidence that low vitamin D levels lead to increased risk of developing rickets, osteoporosis and osteomaloma, 16 cancers (including cancers of breast, ovary, prostate and non-Hodgkin's lymphoma), and other chronic diseases such as psoriasis, diabetes mellitus, hypertension, heart disease, myopathy, multiple sclerosis, schizophrenia, hyperparathyroidism and susceptibility to tuberculosis. The health benefits of UVB seem to outweigh the adverse effects. The risks can be minimized by avoiding sunburn, excess UVR exposure and by attention to dietary factors, such as antioxidants and limiting energy and fat consumption. It is anticipated that increasing attention will be paid to the benefits of UVB radiation and vitamin D and that health guidelines will be revised in the near future.

Entities:  

Year:  2003        PMID: 17156062     DOI: 10.1111/j.1473-2130.2004.00041.x

Source DB:  PubMed          Journal:  J Cosmet Dermatol        ISSN: 1473-2130            Impact factor:   2.696


  7 in total

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2.  Role of vitamin d in the prevention of pancreatic cancer.

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3.  Serum 25-Hydroxyvitamin D Levels and Dry Eye Syndrome: Differential Effects of Vitamin D on Ocular Diseases.

Authors:  Donghyun Jee; Seungbum Kang; Changzheng Yuan; Eunyoung Cho; Jorge G Arroyo
Journal:  PLoS One       Date:  2016-02-19       Impact factor: 3.240

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Authors:  Marwa Mahmoud Abdellah; Engy Mohamed Mostafa; Eman Hassan Salama; Eman Roshdy Mohamed
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5.  Association between serum 25-hydroxyvitamin D levels and myopia in general Korean adults.

Authors:  Byung J Jung; Donghyun Jee
Journal:  Indian J Ophthalmol       Date:  2020-01       Impact factor: 1.848

6.  Population Health Effects of Air Pollution: Fresh Evidence From China Health and Retirement Longitudinal Survey.

Authors:  Wei-Teng Shen; Xuan Yu; Shun-Bin Zhong; Hao-Ran Ge
Journal:  Front Public Health       Date:  2021-12-23

7.  Positive Association between Blood 25-Hydroxyvitamin D Levels and Pterygium after Control for Sunlight Exposure.

Authors:  Donghyun Jee; Eun Chul Kim; Eunyoung Cho; Jorge G Arroyo
Journal:  PLoS One       Date:  2016-06-10       Impact factor: 3.240

  7 in total

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