Literature DB >> 17151233

Telomere dysfunction drives increased mutation by error-prone polymerases Rev1 and zeta in Saccharomyces cerevisiae.

Damon H Meyer1, Adam M Bailis.   

Abstract

Using a model system, we have shown that replicative senescence is accompanied by a 16-fold increase in base substitution and frameshift mutations near a chromosome end. The increase was dependent on error-prone polymerases required for the mutagenic response to DNA lesions that block the replication fork.

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Year:  2006        PMID： 17151233      PMCID： PMC1840081          DOI： 10.1534/genetics.106.068130

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  22 in total

1.  Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae.

Authors:  K Myung; C Chen; R D Kolodner
Journal:  Nature       Date:  2001-06-28       Impact factor: 49.962

Review 2.  Error-prone repair DNA polymerases in prokaryotes and eukaryotes.

Authors:  Myron F Goodman
Journal:  Annu Rev Biochem       Date:  2001-11-09       Impact factor: 23.643

Review 3.  Switching from high-fidelity replicases to low-fidelity lesion-bypass polymerases.

Authors:  Brian S Plosky; Roger Woodgate
Journal:  Curr Opin Genet Dev       Date:  2004-04       Impact factor: 5.578

4.  The distribution of the numbers of mutants in bacterial populations.

Authors:  D E LEA; C A COULSON
Journal:  J Genet       Date:  1949-12       Impact factor: 1.166

5.  Fidelity of human DNA polymerase eta.

Authors:  R E Johnson; M T Washington; S Prakash; L Prakash
Journal:  J Biol Chem       Date:  2000-03-17       Impact factor: 5.157

6.  The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae.

Authors:  Alison J Rattray; Brenda K Shafer; Carolyn B McGill; Jeffrey N Strathern
Journal:  Genetics       Date:  2002-11       Impact factor: 4.562

7.  Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

Authors:  T S Lendvay; D K Morris; J Sah; B Balasubramanian; V Lundblad
Journal:  Genetics       Date:  1996-12       Impact factor: 4.562

8.  Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast.

Authors:  Vincent Pennaneach; Richard D Kolodner
Journal:  Nat Genet       Date:  2004-05-09       Impact factor: 38.330

Review 9.  Genetic instabilities in human cancers.

Authors:  C Lengauer; K W Kinzler; B Vogelstein
Journal:  Nature       Date:  1998-12-17       Impact factor: 49.962

10.  The origin of spontaneous mutation in Saccharomyces cerevisiae.

Authors:  S K Quah; R C von Borstel; P J Hastings
Journal:  Genetics       Date:  1980-12       Impact factor: 4.562
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  10 in total

1.  Mild Telomere Dysfunction as a Force for Altering the Adaptive Potential of Subtelomeric Genes.

Authors:  Jennifer M O Mason; Michael J McEachern
Journal:  Genetics       Date:  2017-12-14       Impact factor: 4.562

2.  AID and Reactive Oxygen Species Can Induce DNA Breaks within Human Chromosomal Translocation Fragile Zones.

Authors:  Nicholas R Pannunzio; Michael R Lieber
Journal:  Mol Cell       Date:  2017-12-07       Impact factor: 17.970

3.  Mating type influences chromosome loss and replicative senescence in telomerase-deficient budding yeast by Dnl4-dependent telomere fusion.

Authors:  Damon H Meyer; Adam M Bailis
Journal:  Mol Microbiol       Date:  2008-07-04       Impact factor: 3.501

Review 4.  Mutation as a stress response and the regulation of evolvability.

Authors:  Rodrigo S Galhardo; P J Hastings; Susan M Rosenberg
Journal:  Crit Rev Biochem Mol Biol       Date:  2007 Sep-Oct       Impact factor: 8.250

5.  Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae.

Authors:  Erica Mito; Janet V Mokhnatkin; Molly C Steele; Victoria L Buettner; Steve S Sommer; Glenn M Manthey; Adam M Bailis
Journal:  Genetics       Date:  2008-08       Impact factor: 4.562

6.  Break-induced replication is highly inaccurate.

Authors:  Angela Deem; Andrea Keszthelyi; Tiffany Blackgrove; Alexandra Vayl; Barbara Coffey; Ruchi Mathur; Andrei Chabes; Anna Malkova
Journal:  PLoS Biol       Date:  2011-02-15       Impact factor: 8.029

Review 7.  The many types of heterogeneity in replicative senescence.

Authors:  Zhou Xu; Maria Teresa Teixeira
Journal:  Yeast       Date:  2019-08-06       Impact factor: 3.239

8.  Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae.

Authors:  Damon H Meyer; Adam M Bailis
Journal:  PLoS One       Date:  2008-10-02       Impact factor: 3.240

9.  Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.

Authors:  Yong Yang; Joan Sterling; Francesca Storici; Michael A Resnick; Dmitry A Gordenin
Journal:  PLoS Genet       Date:  2008-11-21       Impact factor: 5.917

10.  Telomere Dysfunction Triggers Palindrome Formation Independently of Double-Strand Break Repair Mechanisms.

Authors:  Vasil Raykov; Marcus E Marvin; Edward J Louis; Laura Maringele
Journal:  Genetics       Date:  2016-06-22       Impact factor: 4.562
  10 in total

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