Literature DB >> 17140814

Ecstasy and gateway drugs: initiating the use of ecstasy and other drugs.

Lesley W Reid1, Kirk W Elifson, Claire E Sterk.   

Abstract

PURPOSE: The main purposes of this study are to examine whether and to what extent ecstasy use serves as a gateway to the use of such hard drugs as cocaine, heroin, and methamphetamine and compare ages of onset of alcohol and marijuana use and subsequent use of cocaine, heroin, and methamphetamine among young adult ecstasy users.
METHODS: Face-to-face surveys were conducted with 268 young adult ecstasy users in Atlanta, GA. Subjects were solicited by using the community identification process, including targeted sampling and guided recruitment. Data analysis involved discrete-time event-history analysis.
RESULTS: Results suggest that age of onset of ecstasy use influences the initiation of cocaine and methamphetamine use for our sample of active ecstasy users. In addition, alcohol and marijuana use precedes the initiation of cocaine and methamphetamine use, but only marijuana use influences the initiation of heroin use.
CONCLUSIONS: The sequential progression of drug use proposed in the gateway literature is not immutable. Researchers must take into account the changing popularity of drugs over time, such as the emergence of ecstasy use, when identifying patterns of drug-use onset.

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Year:  2006        PMID: 17140814      PMCID: PMC1851690          DOI: 10.1016/j.annepidem.2006.07.013

Source DB:  PubMed          Journal:  Ann Epidemiol        ISSN: 1047-2797            Impact factor:   3.797


  16 in total

Review 1.  Economics of youth drug use, addiction and gateway effects.

Authors:  D Kenkel; A D Mathios; R L Pacula
Journal:  Addiction       Date:  2001-01       Impact factor: 6.526

2.  Drinking and smoking as concurrent predictors of illicit drug use and positive drug attitudes in adolescents.

Authors:  D Best; S Rawaf; J Rowley; K Floyd; V Manning; J Strang
Journal:  Drug Alcohol Depend       Date:  2000-11-01       Impact factor: 4.492

3.  Sequence and stages in patterns of adolescent drug use.

Authors:  D Kandel; R Faust
Journal:  Arch Gen Psychiatry       Date:  1975-07

Review 4.  Sequential progression of substance use among homeless youth: an empirical investigation of the gateway theory.

Authors:  Joshua Aaron Ginzler; Bryan N Cochran; Melanie Domenech-Rodríguez; Ana Mari Cauce; Leslie B Whitbeck
Journal:  Subst Use Misuse       Date:  2003 Feb-May       Impact factor: 2.164

5.  The age of alcohol onset and alcohol, cigarette, and marijuana use patterns: an analysis of drug use progression of young adults in New York State.

Authors:  J Yu; W R Williford
Journal:  Int J Addict       Date:  1992-11

6.  Antecedents of adolescent initiation into stages of drug use: A developmental analysis.

Authors:  D B Kandel; R C Kessler; R Z Margulies
Journal:  J Youth Adolesc       Date:  1978-03

7.  Sequence of drug use among serious drug users: typical vs atypical progression.

Authors:  M E Mackesy-Amiti; M Fendrich; P J Goldstein
Journal:  Drug Alcohol Depend       Date:  1997-05-02       Impact factor: 4.492

8.  Initiation into drug abuse: the pathway from being offered drugs to trying cannabis and progression to intravenous drug abuse.

Authors:  M Stenbacka; P Allebeck; A Romelsjö
Journal:  Scand J Soc Med       Date:  1993-03

9.  The shifting importance of alcohol and marijuana as gateway substances among serious drug abusers.

Authors:  A Golub; B D Johnson
Journal:  J Stud Alcohol       Date:  1994-09

10.  Patterns of drug use from adolescence to young adulthood: III. Predictors of progression.

Authors:  K Yamaguchi; D B Kandel
Journal:  Am J Public Health       Date:  1984-07       Impact factor: 9.308

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  15 in total

Review 1.  Mechanisms of MDMA (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage.

Authors:  Byoung-Joon Song; Kwan-Hoon Moon; Vijay V Upreti; Natalie D Eddington; Insong J Lee
Journal:  Curr Pharm Biotechnol       Date:  2010-08       Impact factor: 2.837

2.  Understanding recreational ecstasy use in the United States: a qualitative inquiry.

Authors:  Masuma Bahora; Claire E Sterk; Kirk W Elifson
Journal:  Int J Drug Policy       Date:  2008-02-20

3.  Use transition between illegal drugs among Brazilian university students.

Authors:  João Mauricio Castaldelli-Maia; Silvia S Martins; Lúcio Garcia de Oliveira; Margriet van Laar; Arthur Guerra de Andrade; Sergio Nicastri
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2013-08-06       Impact factor: 4.328

4.  Poly-Drug Use among Ecstasy Users: Separate, Synergistic, and Indiscriminate Patterns.

Authors:  M Boeri; C Sterk; M Bahora; K Elifson
Journal:  J Drug Issues       Date:  2008-04

5.  Pattern of Methamphetamine Use and the Time Lag to Methamphetamine Dependence.

Authors:  Pongkwan Yimsaard; Michael M Maes; Viroj Verachai; Rasmon Kalayasiri
Journal:  J Addict Med       Date:  2018 Mar/Apr       Impact factor: 3.702

6.  Increased oxidative-modifications of cytosolic proteins in 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-exposed rat liver.

Authors:  Vijay V Upreti; Kwan-Hoon Moon; Li-Rong Yu; Insong J Lee; Natalie D Eddington; Xiaoying Ye; Timothy D Veenstra; Byoung-Joon Song
Journal:  Proteomics       Date:  2010-12-15       Impact factor: 3.984

Review 7.  Post-translational modifications of mitochondrial aldehyde dehydrogenase and biomedical implications.

Authors:  Byoung-Joon Song; Mohamed A Abdelmegeed; Seong-Ho Yoo; Bong-Jo Kim; Sangmee A Jo; Inho Jo; Kwan-Hoon Moon
Journal:  J Proteomics       Date:  2011-05-15       Impact factor: 4.044

8.  Diffusion of Ecstasy in the Electronic Dance Music Scene.

Authors:  Joseph J Palamar
Journal:  Subst Use Misuse       Date:  2020-07-30       Impact factor: 2.164

9.  3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) use and transitions to injection drug use among street-involved youth.

Authors:  Stephanie Lake; Andrew Gaddis; Kenneth W Tupper; Ekaterina Nosova; Kora DeBeck
Journal:  Subst Abus       Date:  2018-11-20       Impact factor: 3.716

10.  Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver.

Authors:  Kwan-Hoon Moon; Vijay V Upreti; Li-Rong Yu; Insong J Lee; Xiaoying Ye; Natalie D Eddington; Timothy D Veenstra; Byoung-Joon Song
Journal:  Proteomics       Date:  2008-09       Impact factor: 3.984

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