Jonathan L Wright1, William J Ellis. 1. Department of Urology, University of Washington Medical Center, Seattle, WA 98195-6510, USA.
Abstract
PURPOSE: Research to improve prostate cancer detection with transrectal ultrasound-guided prostate biopsies has focused on increasing the number of cores and the directing of biopsies laterally. In this study, we describe our experience with the addition of anterior apical biopsies. MATERIALS AND METHODS: A total of 164 consecutive patients with an increased or increasing prostate-specific antigen and/or abnormal digital rectal examination underwent transrectal ultrasound and systematic biopsy. We performed our standard laterally directed sextant biopsies plus additional mid parasagittal plane biopsies at the base and mid-gland, and an anteriorly directed biopsy at the apex. Site-specific detection and tumor characteristics are reported. RESULTS: Prostate cancer was detected in 71 patients (43.3%). The most commonly unique site was the anterior apex. Excluding these biopsies would have missed 17% of the cancers detected. The cancers limited to the anterior apex had tumor characteristics similar to all other cancers detected. CONCLUSION: In our experience, the anterior apical biopsies increase the detection of prostate cancer on transrectal ultrasound-guided biopsies. Further study on incorporating this site into the biopsy scheme is indicated.
PURPOSE: Research to improve prostate cancer detection with transrectal ultrasound-guided prostate biopsies has focused on increasing the number of cores and the directing of biopsies laterally. In this study, we describe our experience with the addition of anterior apical biopsies. MATERIALS AND METHODS: A total of 164 consecutive patients with an increased or increasing prostate-specific antigen and/or abnormal digital rectal examination underwent transrectal ultrasound and systematic biopsy. We performed our standard laterally directed sextant biopsies plus additional mid parasagittal plane biopsies at the base and mid-gland, and an anteriorly directed biopsy at the apex. Site-specific detection and tumor characteristics are reported. RESULTS:Prostate cancer was detected in 71 patients (43.3%). The most commonly unique site was the anterior apex. Excluding these biopsies would have missed 17% of the cancers detected. The cancers limited to the anterior apex had tumor characteristics similar to all other cancers detected. CONCLUSION: In our experience, the anterior apical biopsies increase the detection of prostate cancer on transrectal ultrasound-guided biopsies. Further study on incorporating this site into the biopsy scheme is indicated.
Authors: N Westhoff; F P Siegel; D Hausmann; M Polednik; J von Hardenberg; M S Michel; M Ritter Journal: World J Urol Date: 2016-11-09 Impact factor: 4.226
Authors: Kristin L Granlund; Sui-Seng Tee; Hebert A Vargas; Serge K Lyashchenko; Ed Reznik; Samson Fine; Vincent Laudone; James A Eastham; Karim A Touijer; Victor E Reuter; Mithat Gonen; Ramon E Sosa; Duane Nicholson; YanWei W Guo; Albert P Chen; James Tropp; Fraser Robb; Hedvig Hricak; Kayvan R Keshari Journal: Cell Metab Date: 2019-09-26 Impact factor: 27.287
Authors: Geoffrey A Sonn; Edward Chang; Shyam Natarajan; Daniel J Margolis; Malu Macairan; Patricia Lieu; Jiaoti Huang; Frederick J Dorey; Robert E Reiter; Leonard S Marks Journal: Eur Urol Date: 2013-03-17 Impact factor: 20.096
Authors: Geoffrey A Sonn; Shyam Natarajan; Daniel J A Margolis; Malu MacAiran; Patricia Lieu; Jiaoti Huang; Frederick J Dorey; Leonard S Marks Journal: J Urol Date: 2012-11-14 Impact factor: 7.450
Authors: Daniel N Costa; B Nicolas Bloch; David F Yao; Martin G Sanda; Long Ngo; Elizabeth M Genega; Ivan Pedrosa; William C DeWolf; Neil M Rofsky Journal: Magn Reson Imaging Date: 2013-04-18 Impact factor: 2.546