Literature DB >> 1713690

Biological transport processes and space dimension.

W Nadler1, D L Stein.   

Abstract

We discuss the generic time behavior of reaction-diffusion processes capable of modeling various types of biological transport processes, such as ligand migration in proteins and gating fluctuations in ion channel proteins. The main observable in these two cases, the fraction of unbound ligands and the probability of finding the channel in the closed state, respectively, exhibits an algebraic t-1/2 decay at intermediate times, followed by an exponential cutoff. We provide a simple framework for understanding these observations and explain their ubiquity by showing that these qualitative results are independent of space dimension. We also derive an experimental criterion to distinguish between a one-dimensional process and one whose effective dimension is higher.

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Year:  1991        PMID: 1713690      PMCID: PMC52166          DOI: 10.1073/pnas.88.15.6750

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  19 in total

1.  Reptation theory of ion channel gating.

Authors:  G L Millhauser
Journal:  Biophys J       Date:  1990-04       Impact factor: 4.033

2.  A reevaluation of the mathematical models for simulating single-channel and whole-cell ionic currents.

Authors:  G L Millhauser; R E Oswald
Journal:  Synapse       Date:  1988       Impact factor: 2.562

3.  Rate-amplitude correlation from single-channel records. A hidden structure in ion channel gating kinetics?

Authors:  G L Millhauser; E E Salpeter; R E Oswald
Journal:  Biophys J       Date:  1988-12       Impact factor: 4.033

4.  Diffusion models of ion-channel gating and the origin of power-law distributions from single-channel recording.

Authors:  G L Millhauser; E E Salpeter; R E Oswald
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

5.  Ligand binding to heme proteins: relevance of low-temperature data.

Authors:  A Ansari; E E DiIorio; D D Dlott; H Frauenfelder; I E Iben; P Langer; H Roder; T B Sauke; E Shyamsunder
Journal:  Biochemistry       Date:  1986-06-03       Impact factor: 3.162

6.  Protein states and proteinquakes.

Authors:  A Ansari; J Berendzen; S F Bowne; H Frauenfelder; I E Iben; T B Sauke; E Shyamsunder; R D Young
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

Review 7.  The internal dynamics of globular proteins.

Authors:  M Karplus; J A McCammon
Journal:  CRC Crit Rev Biochem       Date:  1981

8.  Solvent viscosity and protein dynamics.

Authors:  D Beece; L Eisenstein; H Frauenfelder; D Good; M C Marden; L Reinisch; A H Reynolds; L B Sorensen; K T Yue
Journal:  Biochemistry       Date:  1980-11-11       Impact factor: 3.162

9.  Binding of carbon monoxide to isolated hemoglobin chains.

Authors:  N Alberding; S S Chan; L Eisenstein; H Frauenfelder; D Good; I C Gunsalus; T M Nordlund; M F Perutz; A H Reynolds; L B Sorensen
Journal:  Biochemistry       Date:  1978-01-10       Impact factor: 3.162

10.  Rebinding and relaxation in the myoglobin pocket.

Authors:  A Ansari; J Berendzen; D Braunstein; B R Cowen; H Frauenfelder; M K Hong; I E Iben; J B Johnson; P Ormos; T B Sauke
Journal:  Biophys Chem       Date:  1987-05-09       Impact factor: 2.352

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  6 in total

1.  Ion channel gating: a first-passage time analysis of the Kramers type.

Authors:  Igor Goychuk; Peter Hänggi
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-12       Impact factor: 11.205

2.  Fluorescent protein barrel fluctuations and oxygen diffusion pathways in mCherry.

Authors:  Prem P Chapagain; Chola K Regmi; William Castillo
Journal:  J Chem Phys       Date:  2011-12-21       Impact factor: 3.488

3.  Time course of reactions controlled and gated by intramolecular dynamics of proteins: predictions of the model of random walk on fractal lattices.

Authors:  M Kurzynski; K Palacz; P Chelminiak
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-29       Impact factor: 11.205

4.  Stark-effect experiments on photochemical holes in chromoproteins: protoporphyrin IX-substituted myoglobin.

Authors:  J Gafert; J Friedrich; F Parak
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-14       Impact factor: 11.205

5.  Exploring the diffusion of molecular oxygen in the red fluorescent protein mCherry using explicit oxygen molecular dynamics simulations.

Authors:  Chola K Regmi; Yuba R Bhandari; Bernard S Gerstman; Prem P Chapagain
Journal:  J Phys Chem B       Date:  2013-02-14       Impact factor: 2.991

Review 6.  Myristoylation: An Important Protein Modification in the Immune Response.

Authors:  Daniel Ikenna Udenwobele; Ruey-Chyi Su; Sara V Good; Terry Blake Ball; Shailly Varma Shrivastav; Anuraag Shrivastav
Journal:  Front Immunol       Date:  2017-06-30       Impact factor: 7.561

  6 in total

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