| Literature DB >> 17131989 |
Claude J Rogers1, Lisa M Eubanks, Tobin J Dickerson, Kim D Janda.
Abstract
A series of proteins with cocaine esterase ability have been shown to hydrolyze acetylcholine with similar rate enhancements. Docking studies revealed that acetylcholine binds in a similar orientation as cocaine. These results suggest that acetylcholinesterase activity may be inherent to cocaine esterases.Entities:
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Year: 2006 PMID： 17131989 PMCID： PMC2533137 DOI： 10.1021/ja066241+
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419