Literature DB >> 17131108

Beyond blood sugar: the potential of NMR-based metabonomics for type 2 human diabetes, and the horse as a possible model.

Michael S Hodavance1, Sarah L Ralston, István Pelczer.   

Abstract

Metabonomic analysis is a powerful tool for identifying and characterizing metabolic disorders, for example type 2 diabetes and the metabolic syndrome. Nuclear magnetic resonance (NMR) spectroscopy is an essential tool for such analysis, with special benefits. The review assesses the current status and potential of NMR-based metabonomics of type 2 diabetes. The horse is proposed as a possible model for studying this condition and disease. Some examples are shown of horse blood analyses by NMR.

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Year:  2006        PMID： 17131108     DOI： 10.1007/s00216-006-0979-z

Source DB:  PubMed          Journal:  Anal Bioanal Chem        ISSN： 1618-2642            Impact factor:   4.142


  13 in total

1.  Metabolomics reveals attenuation of the SLC6A20 kidney transporter in nonhuman primate and mouse models of type 2 diabetes mellitus.

Authors:  Andrew D Patterson; Jessica A Bonzo; Fei Li; Kristopher W Krausz; Gabriel S Eichler; Sadaf Aslam; Xenia Tigno; John N Weinstein; Barbara C Hansen; Jeffrey R Idle; Frank J Gonzalez
Journal:  J Biol Chem       Date:  2011-04-12       Impact factor: 5.157

Review 2.  Equine clinical genomics: A clinician's primer.

Authors:  M M Brosnahan; S A Brooks; D F Antczak
Journal:  Equine Vet J       Date:  2010-10       Impact factor: 2.888

3.  Interdependence of signal processing and analysis of urine 1H NMR spectra for metabolic profiling.

Authors:  Shucha Zhang; Cheng Zheng; Ian R Lanza; K Sreekumaran Nair; Daniel Raftery; Olga Vitek
Journal:  Anal Chem       Date:  2009-08-01       Impact factor: 6.986

Review 4.  Metabolomics-based methods for early disease diagnostics.

Authors:  G A Nagana Gowda; Shucha Zhang; Haiwei Gu; Vincent Asiago; Narasimhamurthy Shanaiah; Daniel Raftery
Journal:  Expert Rev Mol Diagn       Date:  2008-09       Impact factor: 5.225

5.  Web server suite for complex mixture analysis by covariance NMR.

Authors:  Fengli Zhang; Steven L Robinette; Lei Bruschweiler-Li; Rafael Brüschweiler
Journal:  Magn Reson Chem       Date:  2009-12       Impact factor: 2.447

6.  Correlative and quantitative 1H NMR-based metabolomics reveals specific metabolic pathway disturbances in diabetic rats.

Authors:  Shucha Zhang; G A Nagana Gowda; Vincent Asiago; Narasimhamurthy Shanaiah; Coral Barbas; Daniel Raftery
Journal:  Anal Biochem       Date:  2008-08-20       Impact factor: 3.365

7.  Protein catabolism and high lipid metabolism associated with long-distance exercise are revealed by plasma NMR metabolomics in endurance horses.

Authors:  Laurence Le Moyec; Céline Robert; Mohamed N Triba; Véronique L Billat; Xavier Mata; Laurent Schibler; Eric Barrey
Journal:  PLoS One       Date:  2014-03-21       Impact factor: 3.240

8.  Metabolomic analysis based on 1H-nuclear magnetic resonance spectroscopy metabolic profiles in tuberculous, malignant and transudative pleural effusion.

Authors:  Cheng Wang; Jingjin Peng; Yanling Kuang; Jiaqiang Zhang; Luming Dai
Journal:  Mol Med Rep       Date:  2017-06-12       Impact factor: 2.952

9.  Metabonomics-based study of clinical urine samples in suboptimal health with different syndromes.

Authors:  Hai-Zhen Cui; Li-Min Wang; Xin Zhao; Yue-Yun Liu; Shao-Xian Wang; Xiao-Hong Li; You-Ming Jiang; Jia-Xu Chen
Journal:  Evid Based Complement Alternat Med       Date:  2013-01-17       Impact factor: 2.629

10.  Energetics of endurance exercise in young horses determined by nuclear magnetic resonance metabolomics.

Authors:  Margaux M Luck; Laurence Le Moyec; Eric Barrey; Mohamed N Triba; Nadia Bouchemal; Philippe Savarin; Céline Robert
Journal:  Front Physiol       Date:  2015-07-15       Impact factor: 4.566
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