Literature DB >> 17130579

Probiotics for the prevention of beta cell autoimmunity in children at genetic risk of type 1 diabetes--the PRODIA study.

Martin Ljungberg1, Riita Korpela, Jorma Ilonen, Johnny Ludvigsson, Outi Vaarala.   

Abstract

The final aim of the PRODIA study is to determine whether the use of probiotics during the first 6 months of life decreases the appearance of type 1 diabetes mellitus (T1DM)-associated autoantibodies in children with genetic risk for T1DM. A pilot study including 200 subjects was planned to show whether the use of probiotics during the first 6 months of life is safe and feasible. The prevalence of autoantibodies among the study subjects at 6, 12, and 24 months of age was at levels close to the expected and the clinical follow-up did not either indicate problems in the feasibility of the study.

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Year:  2006        PMID: 17130579     DOI: 10.1196/annals.1375.055

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN: 0077-8923            Impact factor:   5.691


  16 in total

1.  Environmental factors and primary prevention in type 1 diabetes.

Authors:  Jorma Ilonen; Outi Vaarala; Hans K Akerblom; Mikael Knip
Journal:  Pediatr Endocrinol Diabetes Metab       Date:  2009

Review 2.  The 'hygiene hypothesis' for autoimmune and allergic diseases: an update.

Authors:  H Okada; C Kuhn; H Feillet; J-F Bach
Journal:  Clin Exp Immunol       Date:  2010-04       Impact factor: 4.330

Review 3.  Immunomodulation with microbial vaccines to prevent type 1 diabetes mellitus.

Authors:  Nikolai Petrovsky
Journal:  Nat Rev Endocrinol       Date:  2010-03       Impact factor: 43.330

4.  The effects of probiotic bacteria on glycaemic control in overweight men and women: a randomised controlled trial.

Authors:  K L Ivey; J M Hodgson; D A Kerr; J R Lewis; P L Thompson; R L Prince
Journal:  Eur J Clin Nutr       Date:  2014-02-26       Impact factor: 4.016

Review 5.  Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease.

Authors:  M A Atkinson; A Chervonsky
Journal:  Diabetologia       Date:  2012-08-09       Impact factor: 10.122

Review 6.  The hygiene hypothesis in autoimmunity: the role of pathogens and commensals.

Authors:  Jean-François Bach
Journal:  Nat Rev Immunol       Date:  2017-10-16       Impact factor: 53.106

Review 7.  Do bugs control our fate? The influence of the microbiome on autoimmunity.

Authors:  Irene Fung; Jackie P-D Garrett; Anupama Shahane; Mildred Kwan
Journal:  Curr Allergy Asthma Rep       Date:  2012-12       Impact factor: 4.806

8.  Effects of high-AGE beverage on RAGE and VEGF expressions in the liver and kidneys.

Authors:  Takashi Sato; Xuegang Wu; Noriko Shimogaito; Jun-ichi Takino; Sho-ichi Yamagishi; Masayoshi Takeuchi
Journal:  Eur J Nutr       Date:  2008-12-12       Impact factor: 5.614

Review 9.  The role for gut permeability in the pathogenesis of type 1 diabetes--a solid or leaky concept?

Authors:  Xia Li; Mark A Atkinson
Journal:  Pediatr Diabetes       Date:  2015-08-13       Impact factor: 4.866

10.  The Effects of Synbiotic Supplementation on Glycemic Status, Lipid Profile, and Biomarkers of Oxidative Stress in Type 1 Diabetic Patients. A Placebo-Controlled, Double-Blind, Randomized Clinical Trial.

Authors:  Ahmad Zare Javid; Majid Aminzadeh; Mohammad Hosein Haghighi-Zadeh; Mona Jamalvandi
Journal:  Diabetes Metab Syndr Obes       Date:  2020-03-02       Impact factor: 3.168

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