Literature DB >> 17129634

Irradiated volume and the risk of fatal hemoptysis in patients submitted to high dose-rate endobronchial brachytherapy.

Heloisa de Andrade Carvalho1, Silmara Luci Vernúcio Gonçalves, Wilson Pedreira, Marcelo Gervilla Gregório, Isac de Castro, Salim Aisen.   

Abstract

To determine risk factors associated with fatal hemoptysis (FH) in endobronchial high dose-rate brachytherapy (EHDRB) 84 patients treated with EHDRB from January 1991 to June 2002 were studied. Clinical and technical parameters (including treatment volumes) were analyzed. Eight (9.5%) patients died of FH, all but one with recurrent or persistent local disease. Median interval until death due to FH was 4 months versus 6 months for the whole group. The only factor with significant correlation with FH was the 100% isodose volume (V100) (p=0.04). Larger irradiated volumes were related to FH. Analysis of volume parameters is suggested, together with the dose and number of fractions prescribed for each patient.

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Year:  2006        PMID: 17129634     DOI: 10.1016/j.lungcan.2006.10.015

Source DB:  PubMed          Journal:  Lung Cancer        ISSN: 0169-5002            Impact factor:   5.705


  3 in total

1.  A total EQD2 greater than 85 Gy for trachea and main bronchus D2cc being associated with severe late complications after definitive endobronchial brachytherapy.

Authors:  Naoya Murakami; Kazuma Kobayashi; Satoshi Nakamura; Akihisa Wakita; Hiroyuki Okamoto; Keisuke Tsuchida; Tairo Kashihara; Ken Harada; Mayuka Yamada; Shuhei Sekii; Kana Takahashi; Rei Umezawa; Koji Inaba; Yoshinori Ito; Hiroshi Igaki; Jun Itami
Journal:  J Contemp Brachytherapy       Date:  2015-10-13

2.  Definitive carbon ion radiotherapy for tracheobronchial adenoid cystic carcinoma: a preliminary report.

Authors:  Jian Chen; Jingfang Mao; Ningyi Ma; Kai-Liang Wu; Jiade Lu; Guo-Liang Jiang
Journal:  BMC Cancer       Date:  2021-06-26       Impact factor: 4.430

3.  Dose reconstruction technique using non-rigid registration to evaluate spatial correspondence between high-dose region and late radiation toxicity: a case of tracheobronchial stenosis after external beam radiotherapy combined with endotracheal brachytherapy for tracheal cancer.

Authors:  Kazuma Kobayashi; Naoya Murakami; Koji Inaba; Akihisa Wakita; Satoshi Nakamura; Hiroyuki Okamoto; Jun Sato; Rei Umezawa; Kana Takahashi; Hiroshi Igaki; Yoshinori Ito; Naoyuki Shigematsu; Jun Itami
Journal:  J Contemp Brachytherapy       Date:  2016-04-29
  3 in total

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