Literature DB >> 17124428

Role of cytokines in allergic airway inflammation.

Hiroshi Nakajima1, Kiyoshi Takatsu.   

Abstract

Asthma is characterized by intense infiltration of eosinophils and CD4+ T cells into the submucosal tissue of airways. Accumulating evidence indicates that T helper type 2 cell-derived cytokines such as interleukin (IL)-4, IL-5 and IL-13 play critical roles in orchestrating and amplifying allergic inflammation in asthma. In addition, it has been suggested that newly identified cytokines including thymic stromal lymphopoietin, IL-25 and IL-33 are involved in the induction of allergic inflammation in asthma. In this review, we discuss the role of individual cytokines in the pathogenesis of asthma.

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Year:  2006        PMID： 17124428     DOI： 10.1159/000097357

Source DB:  PubMed          Journal:  Int Arch Allergy Immunol        ISSN： 1018-2438            Impact factor:   2.749


  44 in total

1.  Human thymic stromal lymphopoietin enhances expression of CD80 in human CD14+ monocytes/macrophages.

Authors:  Reiji Hirano; Shunji Hasegawa; Kunio Hashimoto; Yasuhiro Haneda; Ayami Ohsaki; Takashi Ichiyama
Journal:  Inflamm Res       Date:  2011-01-28       Impact factor: 4.575

2.  IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway.

Authors:  Kelly M Kroeger; Brandon M Sullivan; Richard M Locksley
Journal:  J Leukoc Biol       Date:  2009-05-18       Impact factor: 4.962

3.  Effects of interleukin-33 on cardiac fibroblast gene expression and activity.

Authors:  Jinyu Zhu; Wayne Carver
Journal:  Cytokine       Date:  2012-03-23       Impact factor: 3.861

4.  Sitagliptin exerts anti-inflammatory and anti-allergic effects in ovalbumin-induced murine model of allergic airway disease.

Authors:  Manar A Nader; Mohammed S El-Awady; Asem A Shalaby; Dina S El-Agamy
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2012-06-26       Impact factor: 3.000

5.  Toxicity testing in the 21st century: a vision and a strategy.

Authors:  Daniel Krewski; Daniel Acosta; Melvin Andersen; Henry Anderson; John C Bailar; Kim Boekelheide; Robert Brent; Gail Charnley; Vivian G Cheung; Sidney Green; Karl T Kelsey; Nancy I Kerkvliet; Abby A Li; Lawrence McCray; Otto Meyer; Reid D Patterson; William Pennie; Robert A Scala; Gina M Solomon; Martin Stephens; James Yager; Lauren Zeise
Journal:  J Toxicol Environ Health B Crit Rev       Date:  2010-02       Impact factor: 6.393

6.  Clinical efficacy of implementing Bio Immune(G)ene MEDicine in the treatment of chronic asthma with the objective of reducing or removing effectively corticosteroid therapy: A novel approach and promising results.

Authors:  Gilbert Glady
Journal:  Exp Ther Med       Date:  2018-04-02       Impact factor: 2.447

7.  IL-12 can alleviate Th17-mediated allergic lung inflammation through induction of pulmonary IL-10 expression.

Authors:  D M Durrant; D W Metzger
Journal:  Mucosal Immunol       Date:  2010-03-17       Impact factor: 7.313

Review 8.  The pharmacological modulation of allergen-induced asthma.

Authors:  L L Ma; Paul M O'Byrne
Journal:  Inflammopharmacology       Date:  2012-10-25       Impact factor: 4.473

9.  Interleukin-18-deficient mice exhibit diminished chronic inflammation and airway remodelling in ovalbumin-induced asthma model.

Authors:  S Yamagata; K Tomita; R Sato; A Niwa; H Higashino; Y Tohda
Journal:  Clin Exp Immunol       Date:  2008-09-23       Impact factor: 4.330

10.  Reduced FcepsilonRI-mediated release of asthma-promoting cytokines and chemokines from human basophils during omalizumab therapy.

Authors:  Janet M Oliver; Christy A Tarleton; Laura Gilmartin; Tereassa Archibeque; Clifford R Qualls; Lorena Diehl; Bridget S Wilson; Mark Schuyler
Journal:  Int Arch Allergy Immunol       Date:  2009-10-22       Impact factor: 2.749
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