Literature DB >> 17123612

Identification of retinal breaks using subretinal trypan blue injection.

Timothy L Jackson1, Anthony S L Kwan, Alistair H Laidlaw, William Aylward.   

Abstract

PURPOSE: To describe the use of subretinal trypan blue to identify retinal breaks during vitrectomy for rhegmatogenous retinal detachment (RD).
DESIGN: Interventional case series. PARTICIPANTS: Five patients with RD in whom no retinal break could be identified by internal search with scleral indentation.
METHODS: Trypan blue 0.15% was injected transretinally into the subretinal space using a 41-gauge cannula designed for macular translocation surgery. Perfluorocarbon heavy liquid was then injected into the vitreous cavity and the eye was rotated such that trypan blue was vented out of the break. The plume of trypan blue was used to identify retinal breaks, or in some cases staining of the break facilitated break detection. Subretinal fluid was then drained through the break or a drainage retinotomy and surgery was completed using standard techniques. MAIN OUTCOME MEASURE: Identification of previously unseen retinal breaks.
RESULTS: This technique successfully identified a retinal break in 4 out of 5 patients. After absorption of the gas tamponade all retinas remained attached with a median visual acuity of 6/12.
CONCLUSION: Failure to identify a retinal break during RD surgery is a well-recognized clinical challenge that may adversely affect outcome. In this setting, chromophore-assisted retinal break detection may be a useful surgical technique.

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Year:  2006        PMID: 17123612     DOI: 10.1016/j.ophtha.2006.05.079

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  10 in total

1.  Trans-scleral dye injection during vitreous surgery to identify clinically undetectable retinal breaks causing retinal detachment.

Authors:  D Gupta; J Ong; R L Burton
Journal:  Eye (Lond)       Date:  2011-06-03       Impact factor: 3.775

2.  Modified subretinal dye extrusion technique (MORE-DETECH): subretinal diluted trypan blue for detecting occult retinal breaks in retinal detachment after endotamponade removal.

Authors:  Sumeet Khanduja; Subijay Sinha; Varun Gogia; Ashish Kakkar; Rajpal Vohra
Journal:  Int Ophthalmol       Date:  2013-02-14       Impact factor: 2.031

3.  Surgical challenges and outcomes of rhegmatogenous retinal detachment in albinism.

Authors:  M K Sinha; J Chhablani; B S Shah; R Narayanan; S Jalali
Journal:  Eye (Lond)       Date:  2015-11-27       Impact factor: 3.775

4.  Pars plana vitrectomy for primary rhegmatogenous retinal detachment.

Authors:  Stephen G Schwartz; Harry W Flynn
Journal:  Clin Ophthalmol       Date:  2008-03

Review 5.  Chromovitrectomy: an update.

Authors:  Flora Hernández; Natalia Alpizar-Alvarez; Lihteh Wu
Journal:  J Ophthalmic Vis Res       Date:  2014-04

6.  Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis.

Authors:  Anna P Salvetti; Maria I Patrício; Alun R Barnard; Harry O Orlans; Doron G Hickey; Robert E MacLaren
Journal:  Transl Vis Sci Technol       Date:  2017-07-10       Impact factor: 3.283

7.  Successful treatment of aggressive posterior retinopathy of prematurity with diode laser in ocular albinism: A case report.

Authors:  Anil B Gangwe; Swapnil M Parchand; Raj Vardhan Azad; Deepshikha Agrawal; Priyavrat Bhatia
Journal:  Indian J Ophthalmol       Date:  2019-06       Impact factor: 1.848

8.  Chromophore-Assisted Retinal Break Detection to Manage Challenging Situations in Retinal Detachment Redo Surgery.

Authors:  Antonio Berarducci; Martina Colasante; Antonio Laborante
Journal:  Case Rep Ophthalmol Med       Date:  2020-11-30

9.  Novel Surgical Pathway for Controlled Access to the Subretinal Space: A Case Series.

Authors:  Khalid Al Sabti; Seemant Raizada
Journal:  Transl Vis Sci Technol       Date:  2022-04-01       Impact factor: 3.283

10.  Scleral buckling with a noncontact wide-angle viewing system in the management of retinal detachment with undetected retinal break: a case report.

Authors:  Mihori Kita; Yukiko Fujii; Naoaki Kawagoe; Sachiyo Hama
Journal:  Clin Ophthalmol       Date:  2013-03-21
  10 in total

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