Literature DB >> 17119150

Altered cardiac myocyte Ca regulation in heart failure.

Donald M Bers1.   

Abstract

Ca is critical in both the electrical and mechanical properties of cardiac myocytes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, there are significant alterations in how myocyte Ca is regulated, and these alterations are critical in dictating both contractile dysfunction and certain cardiac arrhythmias that are characteristic of heart failure.

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Year:  2006        PMID： 17119150     DOI： 10.1152/physiol.00019.2006

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  133 in total

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9.  Restoring redox balance enhances contractility in heart trabeculae from type 2 diabetic rats exposed to high glucose.

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10.  Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout.

Authors:  William E Louch; Karina Hougen; Halvor K Mørk; Fredrik Swift; Jan M Aronsen; Ivar Sjaastad; Henrik M Reims; Borghild Roald; Kristin B Andersson; Geir Christensen; Ole M Sejersted
Journal:  J Physiol       Date:  2009-12-14       Impact factor: 5.182
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