| Literature DB >> 17113993 |
Abstract
In this issue of Chemistry & Biology, Schust et al. report the discovery of a small molecule (Stattic) that inhibits the binding of a high affinity phosphopeptide for the SH2 domain of Stat3. Stattic is a new tool for studying Stat3 signaling and demonstrates that the SH2 domain is not a dead target.Entities:
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Year: 2006 PMID： 17113993 DOI： 10.1016/j.chembiol.2006.11.001
Source DB: PubMed Journal: Chem Biol ISSN： 1074-5521