Literature DB >> 17108275

Use of sequence-based typing for investigation of a case of nosocomial legionellosis.

Sallene Wong1, Kanti Pabbaraju1, Veronica F Burk1, George C Broukhanski2, Julie Fox3,1, Tom Louie4, Manuel W Mah4, Kathryn Bernard5, Peter A G Tilley3,1.   

Abstract

A fatal case of nosocomial legionellosis in a low prevalence region (Calgary, Alberta, Canada) prompted investigation into the source of infection. Hospital water systems contaminated with Legionella pneumophila have been shown to pose a risk to compromised patients. Typing of an L. pneumophila serogroup 1 strain isolated from the patient using sequence-based typing (SBT) and amplified fragment length polymorphism (AFLP) analysis linked it to a persistent and widespread strain isolated from the hospital water system establishing a nosocomial mode of acquisition. Different SBT and AFLP patterns were determined for non-epidemiologically linked cases and isolates from different hospitals.

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Year:  2006        PMID: 17108275     DOI: 10.1099/jmm.0.46754-0

Source DB:  PubMed          Journal:  J Med Microbiol        ISSN: 0022-2615            Impact factor:   2.472


  4 in total

1.  Legionella pneumophila monoclonal antibody subgroups and DNA sequence types isolated in Canada between 1981 and 2009: Laboratory Component of National Surveillance.

Authors:  A R Reimer; S Au; S Schindle; K A Bernard
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2009-12-04       Impact factor: 3.267

2.  Occurrence and distribution of sequence types among Legionella pneumophila strains isolated from patients in Germany: common features and differences to other regions of the world.

Authors:  J Borchardt; J H Helbig; P C Lück
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-01       Impact factor: 3.267

3.  External quality assessment of a DNA sequence-based scheme for epidemiological typing of Legionella pneumophila by an international network of laboratories.

Authors:  Baharak Afshar; Norman K Fry; William Bellamy; Anthony P Underwood; Timothy G Harrison
Journal:  J Clin Microbiol       Date:  2007-08-08       Impact factor: 5.948

4.  Isolation of Legionella pneumophila by Co-culture with Local Ameba, Canada.

Authors:  Rafik Dey; Harley Mount; Alex W Ensminger; Greg J Tyrrell; Linda P Ward; Nicholas J Ashbolt
Journal:  Emerg Infect Dis       Date:  2019-11       Impact factor: 6.883

  4 in total

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