Literature DB >> 17103288

Liver, alcohol and gender.

Christian Müller1.   

Abstract

Gender differences in alcohol-induced liver injury have been well described. Females develop alcoholic liver injury more rapidly and have a lower alcohol toxic threshold than men. The mechanism for this difference is poorly characterized, differences in first-pass metabolism in the stomach, or elimination rate, or alcohol distribution volume in the body have been suggested. In addition, estrogen has a major influence on the susceptibility of Kupffer cells to gut-derived LPS resulting in increased proinflammatory cytokine production, which could be a major contributing factor to the increased risk of women to alcohol-induced liver disease.

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Year:  2006        PMID: 17103288     DOI: 10.1007/s10354-006-0348-8

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN: 0043-5341


  29 in total

Review 1.  Medical consequences of alcohol abuse: is gender a factor?

Authors:  S Schenker
Journal:  Alcohol Clin Exp Res       Date:  1997-02       Impact factor: 3.455

2.  Estrogen is involved in early alcohol-induced liver injury in a rat enteral feeding model.

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Journal:  Hepatology       Date:  2000-01       Impact factor: 17.425

3.  Prediction of risk of liver disease by alcohol intake, sex, and age: a prospective population study.

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Journal:  Hepatology       Date:  1996-05       Impact factor: 17.425

4.  High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism.

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Journal:  N Engl J Med       Date:  1990-01-11       Impact factor: 91.245

5.  Estriol sensitizes rat Kupffer cells via gut-derived endotoxin.

Authors:  N Enomoto; S Yamashina; P Schemmer; C A Rivera; B U Bradford; A Enomoto; D A Brenner; R G Thurman
Journal:  Am J Physiol       Date:  1999-09

6.  Ethanol elimination in males and females: relationship to menstrual cycle and body composition.

Authors:  A W Marshall; D Kingstone; M Boss; M Y Morgan
Journal:  Hepatology       Date:  1983 Sep-Oct       Impact factor: 17.425

7.  Gender differences in alcohol metabolism: relationship to liver volume and effect of adjusting for body mass.

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Journal:  Gastroenterology       Date:  1998-12       Impact factor: 22.682

8.  Hepatic apoptosis and proliferation in male and female rats fed alcohol: role of cytokines.

Authors:  Alessandra Colantoni; Ramazan Idilman; Nicola De Maria; Nancy La Paglia; Joseph Belmonte; Frederick Wezeman; Nicholas Emanuele; David H Van Thiel; Elizabeth J Kovacs; Mary Ann Emanuele
Journal:  Alcohol Clin Exp Res       Date:  2003-07       Impact factor: 3.455

9.  Risk of fatty infiltration or cirrhosis of the liver in relation to ethanol consumption: a case-control study.

Authors:  R A Coates; M L Halliday; J G Rankin; S V Feinman; M M Fisher
Journal:  Clin Invest Med       Date:  1986       Impact factor: 0.825

10.  Prevalence of chronic liver disease in the general population of northern Italy: the Dionysos Study.

Authors:  S Bellentani; C Tiribelli; G Saccoccio; M Sodde; N Fratti; C De Martin; G Cristianini
Journal:  Hepatology       Date:  1994-12       Impact factor: 17.425

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  15 in total

1.  Chronic ethanol feeding accelerates hepatocellular carcinoma progression in a sex-dependent manner in a mouse model of hepatocarcinogenesis.

Authors:  Elizabeth Brandon-Warner; Tracy L Walling; Laura W Schrum; Iain H McKillop
Journal:  Alcohol Clin Exp Res       Date:  2011-10-21       Impact factor: 3.455

2.  Heavy alcohol use and premature death from hepatocellular carcinoma in the United States, 1999-2006.

Authors:  Chuanhui Dong; Young-Hee Yoon; Chiung M Chen; Hsiao-Ye Yi
Journal:  J Stud Alcohol Drugs       Date:  2011-11       Impact factor: 2.582

3.  Sex differences in opisthorchiosis and the development of cholangiocarcinoma in Syrian hamster model.

Authors:  Pakkayanee Sudsarn; Nadchanan Wongchalee; Thidarut Boonmars; Porntip Laummaunwai; Yaovaluk Chamgramol; Chawalit Pairojkul; Amornrat Juasook; Sirintip Boonjaraspinyo
Journal:  Parasitol Res       Date:  2013-12-07       Impact factor: 2.289

Review 4.  Female gender in the setting of liver transplantation.

Authors:  Kryssia Isabel Rodríguez-Castro; Eleonora De Martin; Martina Gambato; Silvia Lazzaro; Erica Villa; Patrizia Burra
Journal:  World J Transplant       Date:  2014-12-24

5.  Effect of oophorectomy and exogenous estrogen replacement on liver injury in experimental obstructive jaundice.

Authors:  Hamdi Bulent Ucan; Mehmet Kaplan; Bulent Salman; Utku Yilmaz; B-Bulent Mentes; Cemalettin Aybay
Journal:  World J Gastroenterol       Date:  2008-05-14       Impact factor: 5.742

6.  Airborne exposure to chemical substances in hairdresser salons.

Authors:  Elena Ronda; Bjorg Eli Hollund; Bente E Moen
Journal:  Environ Monit Assess       Date:  2008-05-16       Impact factor: 2.513

7.  Silibinin (Milk Thistle) potentiates ethanol-dependent hepatocellular carcinoma progression in male mice.

Authors:  Elizabeth Brandon-Warner; Ashley L Eheim; David M Foureau; Tracy L Walling; Laura W Schrum; Iain H McKillop
Journal:  Cancer Lett       Date:  2012-08-01       Impact factor: 8.679

8.  Genetic polymorphism at codon 10 of the transforming growth factor-β1 gene in patients with alcoholic liver cirrhosis.

Authors:  Jong Joon Lee; Soo Kyung Park; Oh Sang Kwon; In Sik Won; Dong Kyu Kim; Young Kul Jung; Yang Suh Ku; Yun Soo Kim; Duck Joo Choi; Ju Hyun Kim
Journal:  Korean J Hepatol       Date:  2011-03

9.  Prognostic Significance of the Systemic Inflammatory and Immune Balance in Alcoholic Liver Disease with a Focus on Gender-Related Differences.

Authors:  Beata Kasztelan-Szczerbińska; Agata Surdacka; Krzysztof Celiński; Jacek Roliński; Agnieszka Zwolak; Sławomir Miącz; Mariusz Szczerbiński
Journal:  PLoS One       Date:  2015-06-24       Impact factor: 3.240

Review 10.  A mini-review of the rodent models for alcoholic liver disease: shortcomings, application, and future prospects.

Authors:  Shi-Xuan Liu; Yan-Chao Du; Tao Zeng
Journal:  Toxicol Res (Camb)       Date:  2021-05-10       Impact factor: 3.524

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