OBJECTIVE: C-reactive protein (CRP) is a reliable laboratory test that is useful in distinguishing between viral and bacterial infection. Although widely used, blood sampling and the need for a well-organized laboratory are limiting factors. Recently, a rapid test for serum CRP (QuickRead CRP) has been developed that can use both venous and capillary blood. The aim of this study was to use QuickRead CRP in our Pediatric Emergency Department and to compare this method with the standard laboratory determination (CRP-lab). MATERIAL AND METHODS: All children with fever were given a quick CRP test simultaneously with venous (CRP-V) and capillary blood samples (CRP-C). A total of 127 children were included in the study (median age 2.5 years). RESULTS: The QuickRead CRP test had an excellent correlation with the standard biochemical determination (CRP-lab). More importantly, there was no difference in determination of CRP in the venous and capillary blood samples. Finally, there was no significant intra-assay variability. CONCLUSIONS: The QuickRead CRP test is easy to use, provides reliable results and reduces the need for antibacterial therapy.
OBJECTIVE:C-reactive protein (CRP) is a reliable laboratory test that is useful in distinguishing between viral and bacterial infection. Although widely used, blood sampling and the need for a well-organized laboratory are limiting factors. Recently, a rapid test for serum CRP (QuickRead CRP) has been developed that can use both venous and capillary blood. The aim of this study was to use QuickRead CRP in our Pediatric Emergency Department and to compare this method with the standard laboratory determination (CRP-lab). MATERIAL AND METHODS: All children with fever were given a quick CRP test simultaneously with venous (CRP-V) and capillary blood samples (CRP-C). A total of 127 children were included in the study (median age 2.5 years). RESULTS: The QuickRead CRP test had an excellent correlation with the standard biochemical determination (CRP-lab). More importantly, there was no difference in determination of CRP in the venous and capillary blood samples. Finally, there was no significant intra-assay variability. CONCLUSIONS: The QuickRead CRP test is easy to use, provides reliable results and reduces the need for antibacterial therapy.
Authors: Veerle Matheeussen; Viviane Van Hoof; Katherine Loens; Christine Lammens; Anouk Vanderstraeten; Samuel Coenen; Chris C Butler; Paul Little; Theo J M Verheij; Herman Goossens; Margareta Ieven Journal: Eur J Clin Microbiol Infect Dis Date: 2018-05-10 Impact factor: 3.267