Literature DB >> 17095704

A scaleable and defined system for generating neural stem cells from human embryonic stem cells.

Alexis J Joannides1, Christelle Fiore-Hériché, Alysia A Battersby, Pandula Athauda-Arachchi, Isabelle A Bouhon, Lydia Williams, Kristine Westmore, Paul J Kemp, Alastair Compston, Nicholas D Allen, Siddharthan Chandran.   

Abstract

The ability to differentiate human ESCs (hESCs) to defined lineages in a totally controlled manner is fundamental to developing cell-based therapies and studying human developmental mechanisms. We report a novel, scaleable, and widely applicable system for deriving and propagating neural stem cells from hESCs without the use of animal products, proprietary formulations, or genetic manipulation. This system provides a definitive platform for studying human neural development and has potential therapeutic implications.

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Mesh：

Year:  2006        PMID： 17095704     DOI： 10.1634/stemcells.2006-0562

Source DB:  PubMed          Journal:  Stem Cells        ISSN： 1066-5099            Impact factor:   6.277


  44 in total

Review 1.  Using human pluripotent stem cells to untangle neurodegenerative disease mechanisms.

Authors:  Brigitte Malgrange; Laurence Borgs; Benjamin Grobarczyk; Audrey Purnelle; Patricia Ernst; Gustave Moonen; Laurent Nguyen
Journal:  Cell Mol Life Sci       Date:  2010-10-26       Impact factor: 9.261

2.  Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration.

Authors:  Giles E Hardingham; Rickie Patani; Paul Baxter; David J Wyllie; Siddharthan Chandran
Journal:  Mol Neurobiol       Date:  2010-04-30       Impact factor: 5.590

3.  Neonatal desensitization allows long-term survival of neural xenotransplants without immunosuppression.

Authors:  Claire M Kelly; Sophie V Precious; Caroline Scherf; Richard Penketh; Nazar N Amso; Alysia Battersby; Nicholas D Allen; Stephen B Dunnett; Anne E Rosser
Journal:  Nat Methods       Date:  2009-03-08       Impact factor: 28.547

4.  Investigating synapse formation and function using human pluripotent stem cell-derived neurons.

Authors:  Ji-Eun Kim; Matthew L O'Sullivan; Christopher A Sanchez; Minju Hwang; Mason A Israel; Kristen Brennand; Thomas J Deerinck; Lawrence S B Goldstein; Fred H Gage; Mark H Ellisman; Anirvan Ghosh
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-28       Impact factor: 11.205

5.  Standardized generation and differentiation of neural precursor cells from human pluripotent stem cells.

Authors:  O A Kozhich; R S Hamilton; B S Mallon
Journal:  Stem Cell Rev Rep       Date:  2013-08       Impact factor: 5.739

6.  Nitric oxide signaling and neural stem cell differentiation in peripheral nerve regeneration.

Authors:  Jessica Tao Li; Chandra Somasundaram; Ka Bian; Weijun Xiong; Faiz Mahmooduddin; Rahul K Nath; Ferid Murad
Journal:  Eplasty       Date:  2010-06-14

Review 7.  Concise review: Kidney stem/progenitor cells: differentiate, sort out, or reprogram?

Authors:  Oren Pleniceanu; Orit Harari-Steinberg; Benjamin Dekel
Journal:  Stem Cells       Date:  2010-09       Impact factor: 6.277

8.  Molecular stages of rapid and uniform neuralization of human embryonic stem cells.

Authors:  R Bajpai; G Coppola; M Kaul; M Talantova; F Cimadamore; M Nilbratt; D H Geschwind; S A Lipton; A V Terskikh
Journal:  Cell Death Differ       Date:  2009-03-13       Impact factor: 15.828

9.  Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity.

Authors:  Rickie Patani; Alastair Compston; Clare A Puddifoot; David J A Wyllie; Giles E Hardingham; Nicholas D Allen; Siddharthan Chandran
Journal:  PLoS One       Date:  2009-10-06       Impact factor: 3.240

Review 10.  Human embryonic stem cell differentiation toward regional specific neural precursors.

Authors:  Slaven Erceg; Mohammad Ronaghi; Miodrag Stojković
Journal:  Stem Cells       Date:  2009-01       Impact factor: 6.277
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