Literature DB >> 17094238

BioDash: a Semantic Web dashboard for drug development.

Eric K Neumann1, Dennis Quan.   

Abstract

A researcher's current scientific understanding is assembled from multiple sources of facts and knowledge, along with beliefs and hypotheses of their interpretations. A comprehensive and structured aggregation of all the relevant components is to-date not possible using standard database technologies, nor is it obvious how to include beliefs, such as models and hypotheses into such a bundle. When such information is required as the basis for important decision-making (e.g., in drug discovery), scientists often resort to using commercial presentation applications. This is sub-optimal for the effective use of knowledge, and alternatives that support the inclusion of meaning are urgently needed. This paper describes a prototype Semantic Web application, BioDash, which attempts to aggregate heterogeneous yet related facts and statements (using an RDF model) into an intuitive, visually descriptive and interactive display.

Mesh:

Year:  2006        PMID: 17094238

Source DB:  PubMed          Journal:  Pac Symp Biocomput        ISSN: 2335-6928


  13 in total

1.  Using web ontology language to integrate heterogeneous databases in the neurosciences.

Authors:  Hugo Y K Lam; Luis Marenco; Gordon M Shepherd; Perry L Miller; Kei-Hoi Cheung
Journal:  AMIA Annu Symp Proc       Date:  2006

2.  HCLS 2.0/3.0: health care and life sciences data mashup using Web 2.0/3.0.

Authors:  Kei-Hoi Cheung; Kevin Y Yip; Jeffrey P Townsend; Matthew Scotch
Journal:  J Biomed Inform       Date:  2008-04-11       Impact factor: 6.317

3.  semCDI: a query formulation for semantic data integration in caBIG.

Authors:  E Patrick Shironoshita; Yves R Jean-Mary; Ray M Bradley; Mansur R Kabuka
Journal:  J Am Med Inform Assoc       Date:  2008-04-24       Impact factor: 4.497

4.  Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data.

Authors:  Bin Chen; Xiao Dong; Dazhi Jiao; Huijun Wang; Qian Zhu; Ying Ding; David J Wild
Journal:  BMC Bioinformatics       Date:  2010-05-17       Impact factor: 3.169

Review 5.  Life Sciences and the web: a new era for collaboration.

Authors:  Jonathan A Sagotsky; Le Zhang; Zhihui Wang; Sean Martin; Thomas S Deisboeck
Journal:  Mol Syst Biol       Date:  2008-07-01       Impact factor: 11.429

Review 6.  Advancing translational research with the Semantic Web.

Authors:  Alan Ruttenberg; Tim Clark; William Bug; Matthias Samwald; Olivier Bodenreider; Helen Chen; Donald Doherty; Kerstin Forsberg; Yong Gao; Vipul Kashyap; June Kinoshita; Joanne Luciano; M Scott Marshall; Chimezie Ogbuji; Jonathan Rees; Susie Stephens; Gwendolyn T Wong; Elizabeth Wu; Davide Zaccagnini; Tonya Hongsermeier; Eric Neumann; Ivan Herman; Kei-Hoi Cheung
Journal:  BMC Bioinformatics       Date:  2007-05-09       Impact factor: 3.169

7.  RDFScape: Semantic Web meets systems biology.

Authors:  Andrea Splendiani
Journal:  BMC Bioinformatics       Date:  2008-04-25       Impact factor: 3.169

8.  BioGateway: a semantic systems biology tool for the life sciences.

Authors:  Erick Antezana; Ward Blondé; Mikel Egaña; Alistair Rutherford; Robert Stevens; Bernard De Baets; Vladimir Mironov; Martin Kuiper
Journal:  BMC Bioinformatics       Date:  2009-10-01       Impact factor: 3.169

9.  GORouter: an RDF model for providing semantic query and inference services for Gene Ontology and its associations.

Authors:  Qingwei Xu; Yixiang Shi; Qiang Lu; Guoqing Zhang; Qingming Luo; Yixue Li
Journal:  BMC Bioinformatics       Date:  2008       Impact factor: 3.169

10.  A visual dashboard for moving health technologies from "lab to village".

Authors:  Hassan Masum; Peter A Singer
Journal:  J Med Internet Res       Date:  2007-10-22       Impact factor: 5.428

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