Literature DB >> 1709136

Assignment of the gene for human tenascin to the region q32-q34 of chromosome 9.

M Rocchi1, N Archidiacono, G Romeo, M Saginati, L Zardi.   

Abstract

Tenascin (TN) is a hexameric extracellular matrix glycoprotein that is highly expressed in solid tumors but has a restricted distribution in normal adult tissues. Each TN subunit is composed of segments with high homology to the sequences of epidermal growth factor, fibronectin and fibrinogen. Furthermore, it has been suggested that TN could modulate epithelial-mesenchymal and neuronal-glial interactions. Here, using a cDNA probe to human TN, we have carried out Southern blot analysis of the genomic DNAs from a panel of human-hamster somatic cell hybrids carrying different complements of human chromosomes. The results demonstrate that the human TN gene is located on chromosome 9. Furthermore, in situ hybridization studies demonstrate that human TN is located at 9q32-q34.

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Year:  1991        PMID： 1709136     DOI： 10.1007/bf00201554

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  18 in total

1.  Two contrary functions of tenascin: dissection of the active sites by recombinant tenascin fragments.

Authors:  J Spring; K Beck; R Chiquet-Ehrismann
Journal:  Cell       Date:  1989-10-20       Impact factor: 41.582

Review 2.  Tenascin: a hexameric adhesive glycoprotein.

Authors:  P G Natali; L Zardi
Journal:  Int J Cancer Suppl       Date:  1989

3.  An alternatively spliced region of the human hexabrachion contains a repeat of potential N-glycosylation sites.

Authors:  J R Gulcher; D E Nies; L S Marton; K Stefansson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-03       Impact factor: 11.205

4.  Mapping through somatic cell hybrids and cDNA probes of protein C to chromosome 2, factor X to chromosome 13, and alpha 1-acid glycoprotein to chromosome 9.

Authors:  M Rocchi; L Roncuzzi; R Santamaria; N Archidiacono; L Dente; G Romeo
Journal:  Hum Genet       Date:  1986-09       Impact factor: 4.132

5.  X chromosome replication patterns in a case of X;9 balanced translocation.

Authors:  G Filippi; V Pecile; N Archidiacono; E Baragino; G Auber; M Rocchi
Journal:  J Med Genet       Date:  1983-12       Impact factor: 6.318

6.  Participation of tenascin and transforming growth factor-beta in reciprocal epithelial-mesenchymal interactions of MCF7 cells and fibroblasts.

Authors:  R Chiquet-Ehrismann; P Kalla; C A Pearson
Journal:  Cancer Res       Date:  1989-08-01       Impact factor: 12.701

Review 7.  What distinguishes tenascin from fibronectin?

Authors:  R Chiquet-Ehrismann
Journal:  FASEB J       Date:  1990-06       Impact factor: 5.191

8.  Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies.

Authors:  A Siri; B Carnemolla; M Saginati; A Leprini; G Casari; F Baralle; L Zardi
Journal:  Nucleic Acids Res       Date:  1991-02-11       Impact factor: 16.971

9.  Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol.

Authors:  R L Davidson; P S Gerald
Journal:  Somatic Cell Genet       Date:  1976-03

10.  Isolation of mammalian cell mutants deficient in glucose-6-phosphate dehydrogenase activity: linkage to hypoxanthine phosphoribosyl transferase.

Authors:  M Rosenstraus; L A Chasin
Journal:  Proc Natl Acad Sci U S A       Date:  1975-02       Impact factor: 11.205
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  4 in total

Review 1.  The genetics of sports injuries and athletic performance.

Authors:  Nicola Maffulli; Katia Margiotti; Umile Giuseppe Longo; Mattia Loppini; Vito Michele Fazio; Vincenzo Denaro
Journal:  Muscles Ligaments Tendons J       Date:  2013-08-11

2.  Comparative mapping of mouse chromosome 4 and human chromosome 9: Lv, Orm, and Hxb are closely linked on mouse chromosome 4.

Authors:  A Pilz; H Moseley; J Peters; C Abbott
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 3.  Matricellular protein tenascin C: Implications in glioma progression, gliomagenesis, and treatment.

Authors:  Zaixiang Fu; Ganggui Zhu; Chao Luo; Zihang Chen; Zhangqi Dou; Yike Chen; Chen Zhong; Sheng Su; Fuyi Liu
Journal:  Front Oncol       Date:  2022-08-12       Impact factor: 5.738

Review 4.  Tenascin-C: Form versus function.

Authors:  Sean P Giblin; Kim S Midwood
Journal:  Cell Adh Migr       Date:  2015       Impact factor: 3.405
  4 in total

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