BACKGROUND AND AIMS: We analyzed the clinicopathologic features of node-positive gastric carcinoma patients who were long-term survivors (5 years or longer) and evaluated the predictive factors associated with long-term survival. PATIENTS AND METHODS: Of 554 node-positive gastric carcinoma patients with curative resection, 161 (29.1%) were long-term survivors, and 393 died of the disease before 5 years. RESULTS: The long-term survivor group had a recurrence rate of 16.1%, while the recurrence rate was 95.4% in the short-term survivor group (P < 0.05). The mean tumor size in the long-term survivors (4.5 cm) was significantly smaller than that in the short-term survivors (5.3 cm; P < 0.001). A depth of invasion greater than T3 was found more frequently in the short-term survivor group (88.1%) than in the long-term survivor group (70.1%; P < 0.001). Using Cox's proportional hazard regression model, the only factor found to be an independent, statistically significant prognostic parameter was tumor size (risk ratio, 0.301; 95% confidence interval, 0.10-0.88; P < 0.05). CONCLUSION: The tumor size emerged as the only independent, significant factor for the prediction of long-term survival in node-positive gastric carcinoma patients with curative resection.
BACKGROUND AND AIMS: We analyzed the clinicopathologic features of node-positive gastric carcinomapatients who were long-term survivors (5 years or longer) and evaluated the predictive factors associated with long-term survival. PATIENTS AND METHODS: Of 554 node-positive gastric carcinomapatients with curative resection, 161 (29.1%) were long-term survivors, and 393 died of the disease before 5 years. RESULTS: The long-term survivor group had a recurrence rate of 16.1%, while the recurrence rate was 95.4% in the short-term survivor group (P < 0.05). The mean tumor size in the long-term survivors (4.5 cm) was significantly smaller than that in the short-term survivors (5.3 cm; P < 0.001). A depth of invasion greater than T3 was found more frequently in the short-term survivor group (88.1%) than in the long-term survivor group (70.1%; P < 0.001). Using Cox's proportional hazard regression model, the only factor found to be an independent, statistically significant prognostic parameter was tumor size (risk ratio, 0.301; 95% confidence interval, 0.10-0.88; P < 0.05). CONCLUSION: The tumor size emerged as the only independent, significant factor for the prediction of long-term survival in node-positive gastric carcinomapatients with curative resection.
Authors: T Mitsudomi; T Matsusaka; K Wakasugi; M Takenaka; K Kume; Y Fujinaga; H Teraoka; A Iwashita Journal: World J Surg Date: 1989 Mar-Apr Impact factor: 3.352
Authors: K Nakamura; T Ueyama; T Yao; Z X Xuan; K Ambe; Y Adachi; Y Yakeishi; A Matsukuma; M Enjoji Journal: Cancer Date: 1992-09-01 Impact factor: 6.860
Authors: Mohammad Mobayed; Lance K Heilbrun; Anthony F Shields; Tara Washington; Raghu Venkatramanamoorthy; Philip A Philip; Bassel F El-Rayes Journal: Case Rep Oncol Date: 2009-11-21