Literature DB >> 17088037

Anti-arthritic activity of a biopolymeric fraction from Euphorbia tirucalli.

Sarang Bani1, Anpurna Kaul, Beenish Khan, Vijay Kumar Gupta, Naresh Kumar Satti, Krishan Avtar Suri, Ghulam Nabi Qazi.   

Abstract

The present study was undertaken to investigate the anti-arthritic activity of a biopolymeric fraction (BET) from plant Euphorbia tirucalli Boiss (Euphorbiaceae). The fraction showed dose dependent anti-arthritic activity and also showed in vivo immunomodulatory capacity being a major component in inhibiting arthritis. It caused suppression of CD4(+) and CD8(+) T cells, inhibition of intracellular Interleukin-2 (IL-2) and Interferon-gamma (IFN-gamma) by flowcytometry. It inhibited vascular permeability and the migration of leucocytes at the site of the insult. The oral LD(0) in both rats and mice was more than 2000 mg/kg.

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Year:  2006        PMID： 17088037     DOI： 10.1016/j.jep.2006.09.021

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  13 in total

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3.  EFFECTS OF TOPICAL TREATMENT WITH EUPHORBIA TIRUCALLI LATEX ON THE SURVIVAL AND INTESTINAL ADHESIONS IN RATS WITH EXPERIMENTAL PERITONITIS.

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Journal:  Arq Bras Cir Dig       Date:  2015 Nov-Dec

4.  Inhibitory effects of Euphorbia tirucalli latex on murine B16/F10 melanoma cells and lung metastasis.

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5.  Ethnopharmacological survey among migrants living in the Southeast Atlantic Forest of Diadema, São Paulo, Brazil.

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6.  Preventive and therapeutic euphol treatment attenuates experimental colitis in mice.

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7.  Anti-inflammatory and antiarthritic activity of anthraquinone derivatives in rodents.

Authors:  Ajay D Kshirsagar; Prashant V Panchal; Uday N Harle; Rabindra K Nanda; Haidarali M Shaikh
Journal:  Int J Inflam       Date:  2014-12-24

8.  Identification of Phenolic Compounds and Evaluation of Antioxidant and Antimicrobial Properties of Euphorbia Tirucalli L.

Authors:  Keline Medeiros de Araújo; Alessandro de Lima; Jurandy do N Silva; Larissa L Rodrigues; Adriany G N Amorim; Patrick V Quelemes; Raimunda C Dos Santos; Jefferson A Rocha; Éryka O de Andrades; José Roberto S A Leite; Jorge Mancini-Filho; Reginaldo Almeida da Trindade
Journal:  Antioxidants (Basel)       Date:  2014-03-17

9.  Anti-Arthritic Activity of Bartogenic Acid Isolated from Fruits of Barringtonia racemosa Roxb. (Lecythidaceae).

Authors:  Kalpesh Ramdas Patil; Chandragouda Raosaheb Patil; Ramchandra Baburao Jadhav; Vallabh Krishnalal Mahajan; Prabhakar Raosaheb Patil; Pradeep Sampatrao Gaikwad
Journal:  Evid Based Complement Alternat Med       Date:  2011-02-20       Impact factor: 2.629

10.  Comparative Transcriptome Analysis Identifies Putative Genes Involved in Steroid Biosynthesis in Euphorbia tirucalli.

Authors:  Weibo Qiao; Changfu Li; Isidore Mosongo; Qin Liang; Mengdi Liu; Xin Wang
Journal:  Genes (Basel)       Date:  2018-01-15       Impact factor: 4.096
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