PURPOSE: To evaluate adverse effects in patients undergoing fundus fluorescein angiography (FA), and to assess the level of these adverse effects in hypertensive and elderly patients. METHOD: We carried out a retrospective study of 358 patients undergoing FA. They were assessed for adverse effects and their relationship to medical history, pre- and post-FA blood pressure and age. RESULTS: The overall adverse reaction rate (AR) was 11.2%, the majority (80%) of which involved nausea. There were no mortalities and no cases of anaphylaxis or cardiac arrest. Hypertension (systolic or diastolic) did not increase the AR. Interestingly, raised initial systolic blood pressure (BP) > or = 160 showed a statistically significant decreased AR compared with that for BP < 160 (7% versus 15%, respectively; p = 0.04). There was no statistical correlation between AR and age. CONCLUSIONS: FA is a relatively safe procedure, but serious side-effects have been reported in the past and therefore adequate measures need to be in place to cope with such emergencies. In our study, there was no increase in the incidence of adverse effects in patients who were hypertensive or elderly. Therefore, these patients should not be denied an important diagnostic procedure that may improve their quality of life purely because of hypertension or age.
PURPOSE: To evaluate adverse effects in patients undergoing fundus fluorescein angiography (FA), and to assess the level of these adverse effects in hypertensive and elderly patients. METHOD: We carried out a retrospective study of 358 patients undergoing FA. They were assessed for adverse effects and their relationship to medical history, pre- and post-FA blood pressure and age. RESULTS: The overall adverse reaction rate (AR) was 11.2%, the majority (80%) of which involved nausea. There were no mortalities and no cases of anaphylaxis or cardiac arrest. Hypertension (systolic or diastolic) did not increase the AR. Interestingly, raised initial systolic blood pressure (BP) > or = 160 showed a statistically significant decreased AR compared with that for BP < 160 (7% versus 15%, respectively; p = 0.04). There was no statistical correlation between AR and age. CONCLUSIONS: FA is a relatively safe procedure, but serious side-effects have been reported in the past and therefore adequate measures need to be in place to cope with such emergencies. In our study, there was no increase in the incidence of adverse effects in patients who were hypertensive or elderly. Therefore, these patients should not be denied an important diagnostic procedure that may improve their quality of life purely because of hypertension or age.
Authors: Eduardo A Novais; Mehreen Adhi; Eric M Moult; Ricardo N Louzada; Emily D Cole; Lennart Husvogt; ByungKun Lee; Sabin Dang; Caio V S Regatieri; André J Witkin; Caroline R Baumal; Joachim Hornegger; Vijaysekhar Jayaraman; James G Fujimoto; Jay S Duker; Nadia K Waheed Journal: Am J Ophthalmol Date: 2016-02-04 Impact factor: 5.258
Authors: Ru-Ik Chee; Mrinali P Gupta; Nita G Valikodath; Emily Cole; Anton Orlin; Tala Al-Khaled; Irene Rusu; Samir N Patel; June Han; Vivien Yap; Karyn E Jonas; Peter J Campbell; Michael F Chiang; R V Paul Chan Journal: Ophthalmol Retina Date: 2019-12-16
Authors: Dae Yu Kim; Jeff Fingler; John S Werner; Daniel M Schwartz; Scott E Fraser; Robert J Zawadzki Journal: Biomed Opt Express Date: 2011-05-11 Impact factor: 3.732
Authors: Gökhan Pekel; Semra Acer; Ramazan Yagci; Ebru Nevin Cetin; Mehmet Can Hiraali; Hüseyin Kaya Journal: J Ophthalmol Date: 2013-07-30 Impact factor: 1.909
Authors: Mark Lane; Eric M Moult; Eduardo A Novais; Ricardo N Louzada; Emily D Cole; ByungKun Lee; Lennart Husvogt; Pearse A Keane; Alastair K Denniston; André J Witkin; Caroline R Baumal; James G Fujimoto; Jay S Duker; Nadia K Waheed Journal: Invest Ophthalmol Vis Sci Date: 2016-07-01 Impact factor: 4.799
Authors: Carl B Rebhun; Eric M Moult; Eduardo A Novais; Carlos Moreira-Neto; Stefan B Ploner; Ricardo N Louzada; ByungKun Lee; Caroline R Baumal; James G Fujimoto; Jay S Duker; Nadia K Waheed; Daniela Ferrara Journal: Transl Vis Sci Technol Date: 2017-11-07 Impact factor: 3.283