Literature DB >> 17078679

Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis.

Pei-Lin Wu1, Yu-Lin Hsu, Tian-Shung Wu, K F Bastow, Kuo-Hsiung Lee.   

Abstract

[Structure: see text] Three new compounds, kalanchosides A-C (1-3), as well as five known compounds, were isolated from the aerial parts of Kalanchoe gracilis. The compound structures were determined by spectroscopic methods. All eight isolated compounds showed significant cytotoxic activity against a panel of human tumor cell lines, with potency reaching the nanomolar range. However, only bryophyllin B (8) inhibited HIV replication in H9 lymphocyte cells.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 17078679     DOI： 10.1021/ol061873m

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  14 in total

Review 1.  Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.

Authors:  Kuo-Hsiung Lee
Journal:  J Nat Prod       Date:  2010-03-26       Impact factor: 4.050

Review 2.  Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors:  Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal:  Top Curr Chem (Cham)       Date:  2021-01-05

Review 3.  Witches, potions, and metabolites: an overview from a medicinal perspective.

Authors:  Luana Canzian Llanes; Nathalia Biazotto Sa; Arthur Ribeiro Cenci; Kerolain Faoro Teixeira; Igor Vinícius de França; Lidiane Meier; Aldo Sena de Oliveira
Journal:  RSC Med Chem       Date:  2022-03-30

4.  Complex alpha-pyrones synthesized by a gold-catalyzed coupling reaction.

Authors:  Tuoping Luo; Stuart L Schreiber
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

5.  Antiviral Ability of Kalanchoe gracilis Leaf Extract against Enterovirus 71 and Coxsackievirus A16.

Authors:  Ching-Ying Wang; Shun-Chueh Huang; Yongjun Zhang; Zhen-Rung Lai; Szu-Hao Kung; Yuan-Shiun Chang; Cheng-Wen Lin
Journal:  Evid Based Complement Alternat Med       Date:  2012-05-15       Impact factor: 2.629

6.  Anticancer property of Bryophyllum pinnata (Lam.) Oken. leaf on human cervical cancer cells.

Authors:  Sutapa Mahata; Saurabh Maru; Shirish Shukla; Arvind Pandey; G Mugesh; Bhudev C Das; Alok C Bharti
Journal:  BMC Complement Altern Med       Date:  2012-03-10       Impact factor: 3.659

7.  Kalanchoe tubiflora extract inhibits cell proliferation by affecting the mitotic apparatus.

Authors:  Yi-Jen Hsieh; Ming-Yeh Yang; Yann-Lii Leu; Chinpiao Chen; Chin-Fung Wan; Meng-Ya Chang; Chih-Jui Chang
Journal:  BMC Complement Altern Med       Date:  2012-09-10       Impact factor: 3.659

8.  Chinese herbal medicines as a source of molecules with anti-enterovirus 71 activity.

Authors:  Mengjie Wang; Ling Tao; Hongxi Xu
Journal:  Chin Med       Date:  2016-01-28       Impact factor: 5.455

9.  Phenolic acid content, antioxidant and cytotoxic activities of four Kalanchoë species.

Authors:  Anna Bogucka-Kocka; Christian Zidorn; Małgorzata Kasprzycka; Grażyna Szymczak; Katarzyna Szewczyk
Journal:  Saudi J Biol Sci       Date:  2016-02-01       Impact factor: 4.219

10.  In Vitro Antioxidant and Cytotoxic Activities of 18 Plants from the Erkowit Region, Eastern Sudan.

Authors:  Manar Adam; Gihan O M Elhassan; Sakina Yagi; Fatma Sezer Senol; Ilkay Erdogan Orhan; Abdel Azim Ahmed; Thomas Efferth
Journal:  Nat Prod Bioprospect       Date:  2018-02-16
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.