Literature DB >> 17076693

Predictors of refill non-adherence in patients with heart failure.

Johnson George1, Stephen J Shalansky.   

Abstract

AIM: To identify the health beliefs and patient characteristics associated with medication non-adherence in patients attending a heart failure outpatient clinic.
METHODS: A survey was administered to 350 consenting clinic patients. Questions focused on relevant demographic and clinical characteristics, the Health Belief Model, the Beliefs About Medicines Questionnaire and the Multidimensional Health Locus of Control. Multivariate logistic regression was used to identify independent predictors of refill non-adherence (<90%).
RESULTS: Refill non-adherence was found in 77 (22%) participants. Being a smoker [odds ratio (OR) 2.4, 95% confidence interval (CI) 1.0, 5.8, P = 0.045], two or fewer medication administration times (OR 2.4, 95% CI 1.2, 4.6, P = 0.01), and positive response to 'Have you changed your daily routine to accommodate your heart failure medication schedule' (OR 2.4, 95% CI 1.2, 4.5, P = 0.01) were the independent predictors of refill non-adherence.
CONCLUSION: Perceptions regarding barriers to medication taking and fewer administration times could result in medication non-adherence in congestive heart failure patients. Medication regimens should be designed after accounting for patients' existing routines.

Entities:  

Mesh:

Year:  2006        PMID: 17076693      PMCID: PMC2203237          DOI: 10.1111/j.1365-2125.2006.02800.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


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