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Literature DB >> 17072913

Anti-cytokine vaccines and the immunotherapy of autoimmune diseases.

Abstract

Three papers in this issue of the European Journal of Immunology describe the use of cytokine vaccines to prevent autoimmune disease in experimental animals. The vaccines are based on interleukin 17 (IL-17), a cytokine that has recently been shown to play a central role in inflammation.

Entities: Chemical Disease Gene Species

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Year: 2006 PMID： 17072913 PMCID： PMC2615480 DOI： 10.1002/eji.200636760

Source DB: PubMed Journal: Eur J Immunol ISSN： 0014-2980 Impact factor: 5.532

33 in total

Review 1. The molecular basis of T helper 1 and T helper 2 cell differentiation.

Authors: A O'Garra; N Arai
Journal: Trends Cell Biol Date: 2000-12 Impact factor: 20.808

2. Cutting edge: roles of Toll-like receptor 4 and IL-23 in IL-17 expression in response to Klebsiella pneumoniae infection.

Authors: Kyle I Happel; Mingquan Zheng; Erana Young; Lee J Quinton; Euan Lockhart; Alistair J Ramsay; Judd E Shellito; Jill R Schurr; Gregory J Bagby; Steve Nelson; Jay K Kolls
Journal: J Immunol Date: 2003-05-01 Impact factor: 5.422

3. Understanding the IL-23-IL-17 immune pathway.

Authors: Brent S McKenzie; Robert A Kastelein; Daniel J Cua
Journal: Trends Immunol Date: 2005-11-14 Impact factor: 16.687

Review 4. Rationale and safety of anti-interleukin-23 and anti-interleukin-17A therapy.

Authors: Edward P Bowman; Alissa A Chackerian; Daniel J Cua
Journal: Curr Opin Infect Dis Date: 2006-06 Impact factor: 4.915

Review 5. Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

Authors: R S Liblau; S M Singer; H O McDevitt
Journal: Immunol Today Date: 1995-01

6. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

Authors: Ivaylo I Ivanov; Brent S McKenzie; Liang Zhou; Carlos E Tadokoro; Alice Lepelley; Juan J Lafaille; Daniel J Cua; Dan R Littman
Journal: Cell Date: 2006-09-22 Impact factor: 41.582

Review 7. Regulatory CD4+ T cells and the control of autoimmune disease.

Authors: David C Wraith; Kirsty S Nicolson; Nathaniel T Whitley
Journal: Curr Opin Immunol Date: 2004-12 Impact factor: 7.486

8. T helper cell subsets in insulin-dependent diabetes.

Authors: J D Katz; C Benoist; D Mathis
Journal: Science Date: 1995-05-26 Impact factor: 47.728

9. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.

Authors: Marc Veldhoen; Richard J Hocking; Christopher J Atkins; Richard M Locksley; Brigitta Stockinger
Journal: Immunity Date: 2006-02 Impact factor: 31.745

10. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.

Authors: Caroline Sutton; Corinna Brereton; Brian Keogh; Kingston H G Mills; Ed C Lavelle
Journal: J Exp Med Date: 2006-07-03 Impact factor: 14.307

4 in total