Literature DB >> 7880387

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases.

R S Liblau1, S M Singer, H O McDevitt.   

Abstract

CD4+ T cells play a key role in regulating immune system function. When these regulatory processes go awry, organ-specific autoimmune diseases may develop. Here, Roland Liblau, Steven Singer and Hugh McDevitt explore the thesis that a particular subset of CD4+ T cells, namely T helper 1 (Th1) cells, contributes to the pathogenesis of organ-specific autoimmune diseases, while another subset, Th2 cells, prevents them.

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Year:  1995        PMID: 7880387     DOI: 10.1016/0167-5699(95)80068-9

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  213 in total

Review 1.  Immune mechanisms that regulate susceptibility to autoimmune type I diabetes.

Authors:  B Singh; T L Delovitch
Journal:  Clin Rev Allergy Immunol       Date:  2000-12       Impact factor: 8.667

Review 2.  Treatment of an autoimmune disease with "classical" T cell veto: a proposal.

Authors:  U D Staerz; Y Qi
Journal:  J Clin Immunol       Date:  1999-07       Impact factor: 8.317

Review 3.  The critical role of IL-12 and the IL-12R beta 2 subunit in the generation of pathogenic autoreactive Th1 cells.

Authors:  E M Shevach; J T Chang; B M Segal
Journal:  Springer Semin Immunopathol       Date:  1999

Review 4.  Type 1 and type 2 immune responses in children: their relevance in juvenile arthritis.

Authors:  L R Wedderburn; P Woo
Journal:  Springer Semin Immunopathol       Date:  1999

Review 5.  Cardiac myosin and the TH1/TH2 paradigm in autoimmune myocarditis.

Authors:  M W Cunningham
Journal:  Am J Pathol       Date:  2001-07       Impact factor: 4.307

6.  Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis.

Authors:  T Chitnis; N Najafian; C Benou; A D Salama; M J Grusby; M H Sayegh; S J Khoury
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

7.  Transfer of myelin-specific cells deviated in vitro towards IL-4 production ameliorates ongoing experimental allergic neuritis.

Authors:  C Ekerfelt; C Dahle; R Weissert; M Kvarnström; T Olsson; J Ernerudh
Journal:  Clin Exp Immunol       Date:  2001-01       Impact factor: 4.330

8.  Role of stromal-cell derived factor-1 in the development of autoimmune diseases in non-obese diabetic mice.

Authors:  Khairul Matin; M Abdus Salam; Joynab Akhter; Nobuhiro Hanada; Hidenobu Senpuku
Journal:  Immunology       Date:  2002-10       Impact factor: 7.397

9.  Specific Th2 cells accumulate in the central nervous system of mice protected against experimental autoimmune encephalomyelitis by copolymer 1.

Authors:  R Aharoni; D Teitelbaum; O Leitner; A Meshorer; M Sela; R Arnon
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-10       Impact factor: 11.205

10.  Immunological changes of T helper cells in flow cytometer-sorted CD4+ T cells from patients with Hashimoto's thyroiditis.

Authors:  Yanying Guo; Jazyra Zynat; Shuqing Xing; Liang Xin; Suli Li; Nurongguli Mammat; Yuan Chen; Limin Zhao; Hongli Zhao; Xinling Wang
Journal:  Exp Ther Med       Date:  2018-02-01       Impact factor: 2.447

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