Literature DB >> 1707006

A lectin-binding soluble factor released by CD8+CD57+ lymphocytes from AIDS patients inhibits T cell cytotoxicity.

B Sadat-Sowti1, P Debré, T Idziorek, J M Guillon, F Hadida, E Okzenhendler, C Katlama, C Mayaud, B Autran.   

Abstract

CD8+CD57+ T cells, expanded in peripheral blood lymphocytes of AIDS patients, inhibit the effector phase of HLA-specific cytotoxic T lymphocytes, natural killer and lymphocyte-activated killer cells in a 4-h chromium-release assay. This inhibitory activity present in supernatants of purified sorted CD8+CD57+ cells is mediated by a non-antigen-specific inhibitory factor which is distinct from prostaglandin E2, T cell growth factor (TGF)-beta, latent-TGF-beta, tumor necrosis factor (TNF)-alpha and TNF-beta. Partial biochemical characterization demonstrates that the CD8+CD57+ inhibitory activity (a) is heat, trypsin and acid resistant, (b) binds to concanavalin A columns, indicating its glycosylation state and (c) is mediated by a 20-30-kDa soluble molecule.

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Year:  1991        PMID： 1707006     DOI： 10.1002/eji.1830210329

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  20 in total

1.  Investigation of alpha nascent polypeptide-associated complex functions in a human CD8(+) T cell ex vivo expansion model using antisense oligonucleotides.

Authors:  N Al-Shanti; C G Steward; R J Garland; A W Rowbottom
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Review 2.  The CD8+ T Cell Noncytotoxic Antiviral Responses.

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3.  CD8 lymphocytosis in primary cytomegalovirus (CMV) infection of allograft recipients: expansion of an uncommon CD8+ CD57- subset and its progressive replacement by CD8+ CD57+ T cells.

Authors:  M Labalette; F Salez; F R Pruvot; C Noel; J P Dessaint
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Review 4.  AIDS and the lung: update 1995. 4. Role of the human immunodeficiency virus within the lung.

Authors:  J R Clarke; D S Robinson; R J Coker; R F Miller; D M Mitchell
Journal:  Thorax       Date:  1995-05       Impact factor: 9.139

5.  Purification and partial amino acid sequence of suppressive lymphokine from a CD8+ CD57+ human T hybridoma.

Authors:  C P Quan; S Watanabe; F Vuillier; R Pires; T Matsuo; M Stanislawski; J Pillot; J P Bouvet
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6.  Differential effect of the immunomodulatory hormone somatostatin on replication of human immunodeficiency virus type 1 in CD4+ and CD8+ T lymphocytes.

Authors:  L Mercure; D Phaneuf; M A Wainberg
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7.  Subsets of CD8+, CD57+ cells in normal, healthy individuals: correlations with human cytomegalovirus (HCMV) carrier status, phenotypic and functional analyses.

Authors:  E C Wang; J Taylor-Wiedeman; P Perera; J Fisher; L K Borysiewicz
Journal:  Clin Exp Immunol       Date:  1993-11       Impact factor: 4.330

8.  Early events in immune evasion by the lentivirus maedi-visna occurring within infected lymphoid tissue.

Authors:  P Bird; B Blacklaws; H T Reyburn; D Allen; J Hopkins; D Sargan; I McConnell
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

9.  Prognostic value of CD57(+) T lymphocytes in the peripheral blood of patients with advanced gastric cancer.

Authors:  Junji Akagi; Hideo Baba
Journal:  Int J Clin Oncol       Date:  2008-12-18       Impact factor: 3.402

10.  CD57 expression by T cells in the female genital tract of HIV-zx1 infected women.

Authors:  Lenine J Liebenberg; Adebayo Lawrence Adedeji; Darren P Martin; Pam P Gumbi; Lynette Denny; Jo-Ann S Passmore
Journal:  Clin Immunol       Date:  2010-01-25       Impact factor: 3.969
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