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Literature DB >> 170681

Thermal transitions in human plasma low density lipoproteins.

R J Deckelbaum, G G Shipley, D M Small, R S Lees, P K George.

Abstract

Thermal analysis of human plasma low density lipoproteins reveals a broad reversible transition encompassing body temperature. The calorimetric and x-ray scattering data identify this transition as a cooperation, liquid-crystalline to liquid phase change involving the cholesterol esters in the lipoprotein. This behavior requires the presence of a region rich in cholesterol ester within the lipoprotein.

Entities: Chemical Species

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Year: 1975 PMID： 170681 DOI： 10.1126/science.170681

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

32 in total

1. Three-dimensional structure of low density lipoproteins by electron cryomicroscopy.

Authors: E V Orlova; M B Sherman; W Chiu; H Mowri; L C Smith; A M Gotto
Journal: Proc Natl Acad Sci U S A Date: 1999-07-20 Impact factor: 11.205

2. Human low density lipoprotein: the mystery of core lipid packing.

Authors: Ruth Prassl
Journal: J Lipid Res Date: 2010-12-03 Impact factor: 5.922

3. ¹H NMR spectroscopy quantifies visibility of lipoproteins, subclasses, and lipids at varied temperatures and pressures.

Authors: Daniela Baumstark; Werner Kremer; Alfred Boettcher; Christina Schreier; Paul Sander; Gerd Schmitz; Renate Kirchhoefer; Fritz Huber; Hans Robert Kalbitzer
Journal: J Lipid Res Date: 2019-06-25 Impact factor: 5.922

4. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

Authors: S K Basu; J L Goldstein; G W Anderson; M S Brown
Journal: Proc Natl Acad Sci U S A Date: 1976-09 Impact factor: 11.205

5. Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques.

Authors: S S Katz; G G Shipley; D M Small
Journal: J Clin Invest Date: 1976-07 Impact factor: 14.808

6. LDL binding to lipid emulsion particles: effects of incubation duration, temperature, and addition of plasma subfractions.

Authors: Nathalie F Chanson; Jean-François Lontie; Annette Gulik; Jacqueline Férézou; Yvon A Carpentier
Journal: Lipids Date: 2002-06 Impact factor: 1.880

Thermal transitions in human plasma low density lipoproteins.

1. Three-dimensional structure of low density lipoproteins by electron cryomicroscopy.

2. Human low density lipoprotein: the mystery of core lipid packing.

3. ¹H NMR spectroscopy quantifies visibility of lipoproteins, subclasses, and lipids at varied temperatures and pressures.

4. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

5. Physical chemistry of the lipids of human atherosclerotic lesions. Demonstration of a lesion intermediate between fatty streaks and advanced plaques.

6. LDL binding to lipid emulsion particles: effects of incubation duration, temperature, and addition of plasma subfractions.

7. Molecular organization of the cholesteryl ester droplets in the fatty streaks of human aorta.

8. Cryoelectron microscopy of low density lipoprotein in vitreous ice.

9. Model of human low-density lipoprotein and bound receptor based on cryoEM.

10. The storage lipids in Tangier disease. A physical chemical study.