Literature DB >> 17067325

Effect of pre-hospital advanced life support with rapid sequence intubation on outcome of severe traumatic brain injury.

P Klemen1, S Grmec.   

Abstract

BACKGROUND: The role of pre-hospital trauma care and the effect of pre-hospital rapid sequence intubation (RSI) on patient outcome are still not clear. This study evaluated the impact of pre-hospital trauma care by emergency physicians (EP) on mortality from severe traumatic brain injury (TBI) and a 180-day Glasgow Outcome Scale (GOS).
METHODS: A 48-month parallel non-controlled cohort study compared a group of 64 patients with severe TBI [Glasgow Coma Scale (GCS) < 9; Injury Severity Score (ISS) > 15] who received pre-hospital advanced life support (ALS) with RSI and were transported to the hospital by EPs (EP group), with a group of 60 patients who did not receive pre-hospital ALS with RSI [emergency medical technicians (EMT) group].
RESULTS: There were no significant statistical differences between the groups in age (P= 0.79), mechanism of injury (P= 0.68), gender (P= 0.82), initial GCS (P= 0.63), initial SaO(2) in the field (P= 0.63), initial systolic blood pressure in the field (P= 0.47) and on-scene time (P= 0.41). In the EP group, there was significantly better first hour survival (97% vs. 79%, P= 0.02), first day survival (90% vs. 72%, P= 0.02), better functional outcome (GOS 4-5: 53% vs. 33%, P < 0.01; GOS 2-3: 8% vs. 20%, P < 0.01) and shortened hospitalization time in intensive care unit (ICU) (P= 0.03) and other departments (P= 0.04). In total hospital mortality, we detected no differences between both groups [EP group: 40% (95% CI: 34-45%) vs. EMT group 42% (95% CI: 36-47%, P= 0.76], except in a subgroup of patients with GCS 6-8 where there was significantly lower total hospital mortality in the EP group (24% vs. 78%, P < 0.01).
CONCLUSION: After starting the trauma care system with emergency physicians in our region, there was a decrease in the number of deaths on hospital admission, a reduction in hospital mortality in the GCS group 6-8, a change in the temporal distribution of deaths, an improvement in functional neurological outcome and shortened hospitalization time.

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Year:  2006        PMID: 17067325     DOI: 10.1111/j.1399-6576.2006.01039.x

Source DB:  PubMed          Journal:  Acta Anaesthesiol Scand        ISSN: 0001-5172            Impact factor:   2.105


  21 in total

1.  [Emergency anesthesia, airway management and ventilation in major trauma. Background and key messages of the interdisciplinary S3 guidelines for major trauma patients].

Authors:  G Matthes; M Bernhard; K G Kanz; C Waydhas; M Fischbacher; M Fischer; B W Böttiger
Journal:  Unfallchirurg       Date:  2012-03       Impact factor: 1.000

2.  [Death due to (no) airway. Adverse events by out-of-hospital airway management?].

Authors:  S G Russo; W Zink; H Herff; C H R Wiese
Journal:  Anaesthesist       Date:  2010-10       Impact factor: 1.041

3.  [Performance of prehospital emergency anesthesia and airway management : An online survey].

Authors:  T Warnecke; M Dobbermann; T Becker; M Bernhard; J Hinkelbein
Journal:  Anaesthesist       Date:  2018-06-29       Impact factor: 1.041

4.  Prehospital triage for mass casualty incidents using the META method for early surgical assessment: retrospective validation of a hospital trauma registry.

Authors:  Rodolfo Romero Pareja; Rafael Castro Delgado; Fernando Turégano Fuentes; Israel Jhon Thissard-Vasallo; David Sanz Rosa; Pedro Arcos González
Journal:  Eur J Trauma Emerg Surg       Date:  2018-11-07       Impact factor: 3.693

5.  Location of Road Emergency Stations in Fars Province, Using Spatial Multi-Criteria Decision Making.

Authors:  Ali Goli; Najmeh Ansarizade; Omid Barati; Zahra Kavosi
Journal:  Bull Emerg Trauma       Date:  2015-01

Review 6.  [Emergency anesthesia, airway management and ventilation in major trauma. Background and key messages of the interdisciplinary S3 guidelines for major trauma patients].

Authors:  M Bernhard; G Matthes; K G Kanz; C Waydhas; M Fischbacher; M Fischer; B W Böttiger
Journal:  Anaesthesist       Date:  2011-11       Impact factor: 1.041

7.  Association of Statewide Implementation of the Prehospital Traumatic Brain Injury Treatment Guidelines With Patient Survival Following Traumatic Brain Injury: The Excellence in Prehospital Injury Care (EPIC) Study.

Authors:  Daniel W Spaite; Bentley J Bobrow; Samuel M Keim; Bruce Barnhart; Vatsal Chikani; Joshua B Gaither; Duane Sherrill; Kurt R Denninghoff; Terry Mullins; P David Adelson; Amber D Rice; Chad Viscusi; Chengcheng Hu
Journal:  JAMA Surg       Date:  2019-07-17       Impact factor: 14.766

8.  Risk assessment of pre-hospital trauma airway management by anaesthesiologists using the predictive Bayesian approach.

Authors:  Stephen J M Sollid; Hans Morten Lossius; Anders R Nakstad; Terje Aven; Eldar Søreide
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2010-04-21       Impact factor: 2.953

9.  Effect of Implementing the Out-of-Hospital Traumatic Brain Injury Treatment Guidelines: The Excellence in Prehospital Injury Care for Children Study (EPIC4Kids).

Authors:  Joshua B Gaither; Daniel W Spaite; Bentley J Bobrow; Samuel M Keim; Bruce J Barnhart; Vatsal Chikani; Duane Sherrill; Kurt R Denninghoff; Terry Mullins; P David Adelson; Amber D Rice; Chad Viscusi; Chengcheng Hu
Journal:  Ann Emerg Med       Date:  2020-11-11       Impact factor: 5.721

Review 10.  Is advanced life support better than basic life support in prehospital care? A systematic review.

Authors:  Olli-Pekka Ryynänen; Timo Iirola; Janne Reitala; Heikki Pälve; Antti Malmivaara
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2010-11-23       Impact factor: 2.953

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