Literature DB >> 17067170

Indoleamine 2,3-dioxygenase inhibitors from the Northeastern Pacific Marine Hydroid Garveia annulata.

Alban Pereira1, Eduardo Vottero, Michel Roberge, A Grant Mauk, Raymond J Andersen.   

Abstract

Crude extracts of the marine hydroid Garveia annulata show potent inhibition of indoleamine 2,3-dioxygenase (IDO). Fractionation of the extract led to the identification of the new polyketides annulin C (1), 2-hydroxygarveatin E (4), garveatin E (5), and garvin C (9). Annulins A (2), B (3), and C (1) were found to be submicromolar inhibitors of IDO.

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Year:  2006        PMID： 17067170     DOI： 10.1021/np060111x

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  16 in total

Review 1.  Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy.

Authors:  Aitziber Buqué; Norma Bloy; Fernando Aranda; Isabelle Cremer; Alexander Eggermont; Wolf Hervé Fridman; Jitka Fucikova; Jérôme Galon; Radek Spisek; Eric Tartour; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2016-03-10       Impact factor: 8.110

Review 2.  Trial watch: IDO inhibitors in cancer therapy.

Authors:  Erika Vacchelli; Fernando Aranda; Alexander Eggermont; Catherine Sautès-Fridman; Eric Tartour; Eugene P Kennedy; Michael Platten; Laurence Zitvogel; Guido Kroemer; Lorenzo Galluzzi
Journal:  Oncoimmunology       Date:  2014-12-15       Impact factor: 8.110

Review 3.  Kynurenines in the CNS: recent advances and new questions.

Authors:  László Vécsei; Levente Szalárdy; Ferenc Fülöp; József Toldi
Journal:  Nat Rev Drug Discov       Date:  2012-12-14       Impact factor: 84.694

Review 4.  Recent advances in the discovery of indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.

Authors:  Xiu-Xiu Wang; Si-Yu Sun; Qing-Qing Dong; Xiao-Xiang Wu; Wei Tang; Ya-Qun Xing
Journal:  Medchemcomm       Date:  2019-08-15       Impact factor: 3.597

5.  Macrophilones from the Marine Hydroid Macrorhynchia philippina Can Inhibit ERK Cascade Signaling.

Authors:  Pengcheng Yan; Daniel A Ritt; Katherine Zlotkowski; Heidi R Bokesch; William C Reinhold; John S Schneekloth; Deborah K Morrison; Kirk R Gustafson
Journal:  J Nat Prod       Date:  2018-07-06       Impact factor: 4.050

6.  Structure based development of phenylimidazole-derived inhibitors of indoleamine 2,3-dioxygenase.

Authors:  Sanjeev Kumar; Daniel Jaller; Bhumika Patel; Judith M LaLonde; James B DuHadaway; William P Malachowski; George C Prendergast; Alexander J Muller
Journal:  J Med Chem       Date:  2008-07-30       Impact factor: 7.446

7.  Substrate-protein interaction in human tryptophan dioxygenase: the critical role of H76.

Authors:  Dipanwita Batabyal; Syun-Ru Yeh
Journal:  J Am Chem Soc       Date:  2009-03-11       Impact factor: 15.419

Review 8.  T cell regulatory plasmacytoid dendritic cells expressing indoleamine 2,3 dioxygenase.

Authors:  David J Kahler; Andrew L Mellor
Journal:  Handb Exp Pharmacol       Date:  2009

9.  Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

Authors:  Sanjeev Kumar; William P Malachowski; James B DuHadaway; Judith M LaLonde; Patrick J Carroll; Daniel Jaller; Richard Metz; George C Prendergast; Alexander J Muller
Journal:  J Med Chem       Date:  2008-03-05       Impact factor: 7.446

10.  Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial Activity and Inhibit Indoleamine Dioxygenase.

Authors:  Esther Jortzik; Kathleen Zocher; Antje Isernhagen; Boniface M Mailu; Stefan Rahlfs; Giampietro Viola; Sergio Wittlin; Nicholas H Hunt; Heiko Ihmels; Katja Becker
Journal:  Antimicrob Agents Chemother       Date:  2015-10-12       Impact factor: 5.191
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