Literature DB >> 17067163

Indole alkaloids from Cephalanceropsis gracilis.

Pei-Lin Wu1, Yu-Lin Hsu, Chen-Wei Jao.   

Abstract

Purification of CHCl3 and EtOAc solubles of the MeOH extract of Cephalanceropsis gracilis afforded seven new indole alkaloids, cephalinones A (1), B (2), C (3), and D (4) and cephalandoles A (5), B (6), and C (7), besides eight known compounds. The structures of the new compounds were determined by spectroscopic analysis. All 15 indole alkaloids were evaluated for their cytotoxic effects on MCF-7, NCI-H460, and SF-268 cell lines by the MTT method. Only cephalinone-F (6) showed significant cytotoxicity.

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Year:  2006        PMID： 17067163     DOI： 10.1021/np060395l

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  11 in total

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9.  Oxidative Dearomative Cross-Dehydrogenative Coupling of Indoles with Diverse C-H Nucleophiles: Efficient Approach to 2,2-Disubstituted Indolin-3-ones.

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Authors:  Sohee Kim; Tu Cam Le; Sang-Ah Han; Prima F Hillman; Ahreum Hong; Sunghoon Hwang; Young Eun Du; Hiyoung Kim; Dong-Chan Oh; Sun-Shin Cha; Jihye Lee; Sang-Jip Nam; William Fenical
Journal:  Mar Drugs       Date:  2021-12-29       Impact factor: 5.118
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