Literature DB >> 1706475

Cyclic AMP-independent activation of transcription factor NF-kappa B in HL60 cells by tumor necrosis factors alpha and beta.

H P Hohmann1, R Kolbeck, R Remy, A P van Loon.   

Abstract

No correlation exists in HL60 cells between NF-kappa B activation by tumor necrosis factor (TNF alpha) and TNF beta and intracellular levels of cyclic AMP. Cyclic AMP levels did not increase upon treatment of cells with each of these cytokines, although NF-kappa B was activated. Forskolin or 1-isobutyl-3-methylxanthine drastically increased intracellular levels of cyclic AMP, but neither activated NF-kappa B nor influenced TNF-induced NF-kappa B activation.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1706475      PMCID： PMC359939          DOI： 10.1128/mcb.11.4.2315-2318.1991

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  34 in total

1.  Cloning of a mitogen-inducible gene encoding a kappa B DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs.

Authors:  V Bours; J Villalobos; P R Burd; K Kelly; U Siebenlist
Journal:  Nature       Date:  1990-11-01       Impact factor: 49.962

2.  How does interleukin 1 activate cells? Cyclic AMP and interleukin 1 signal transduction.

Authors:  S B Mizel
Journal:  Immunol Today       Date:  1990-11

3.  Involvement of cyclic AMP-dependent protein kinases in the signal transduction pathway for interleukin-1.

Authors:  M Chedid; S B Mizel
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272

Review 4.  Staurosporine, K-252 and UCN-01: potent but nonspecific inhibitors of protein kinases.

Authors:  U T Rüegg; G M Burgess
Journal:  Trends Pharmacol Sci       Date:  1989-06       Impact factor: 14.819

5.  Expression of the types A and B tumor necrosis factor (TNF) receptors is independently regulated, and both receptors mediate activation of the transcription factor NF-kappa B. TNF alpha is not needed for induction of a biological effect via TNF receptors.

Authors:  H P Hohmann; M Brockhaus; P A Baeuerle; R Remy; R Kolbeck; A P van Loon
Journal:  J Biol Chem       Date:  1990-12-25       Impact factor: 5.157

Review 6.  Cachectin and tumour necrosis factor as two sides of the same biological coin.

Authors:  B Beutler; A Cerami
Journal:  Nature       Date:  1986 Apr 17-23       Impact factor: 49.962

7.  Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: role in the induction of interleukin 6.

Authors:  Y H Zhang; J X Lin; Y K Yip; J Vilcek
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

8.  Cyclic AMP--an intracellular second messenger for interleukin 1.

Authors:  F Shirakawa; U Yamashita; M Chedid; S B Mizel
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

9.  IL-1 signaling for IL-2 production in T cells involves a rise in phosphatidylserine synthesis.

Authors:  M Didier; C Aussel; C Pelassy; M Fehlmann
Journal:  J Immunol       Date:  1988-11-01       Impact factor: 5.422

10.  Maintenance of NF-kappa B activity is dependent on protein synthesis and the continuous presence of external stimuli.

Authors:  H P Hohmann; R Remy; C Scheidereit; A P van Loon
Journal:  Mol Cell Biol       Date:  1991-01       Impact factor: 4.272
View more
  8 in total

Review 1.  Tumor necrosis factor receptors--structure and function.

Authors:  J Rothe; G Gehr; H Loetscher; W Lesslauer
Journal:  Immunol Res       Date:  1992       Impact factor: 2.829

2.  A lymphoid cell-specific nuclear factor containing c-Rel-like proteins preferentially interacts with interleukin-6 kappa B-related motifs whose activities are repressed in lymphoid cells.

Authors:  K Nakayama; H Shimizu; K Mitomo; T Watanabe; S Okamoto; K Yamamoto
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

3.  NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule.

Authors:  R I Scheinman; A A Beg; A S Baldwin
Journal:  Mol Cell Biol       Date:  1993-10       Impact factor: 4.272

4.  Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C.

Authors:  R Lucito; R J Schneider
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

5.  The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation.

Authors:  R M Ten; C V Paya; N Israël; O Le Bail; M G Mattei; J L Virelizier; P Kourilsky; A Israël
Journal:  EMBO J       Date:  1992-01       Impact factor: 11.598

6.  Activation of NF-kappa B in vivo is regulated by multiple phosphorylations.

Authors:  M Naumann; C Scheidereit
Journal:  EMBO J       Date:  1994-10-03       Impact factor: 11.598

7.  Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

Authors:  K Schulze-Osthoff; R Beyaert; V Vandevoorde; G Haegeman; W Fiers
Journal:  EMBO J       Date:  1993-08       Impact factor: 11.598

8.  Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

Authors:  R Schreck; B Meier; D N Männel; W Dröge; P A Baeuerle
Journal:  J Exp Med       Date:  1992-05-01       Impact factor: 14.307
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.