Literature DB >> 17063836

Autologous osteochondral mosaicplasty grafting.

Lajos Bartha1, András Vajda, Zsófia Duska, Husam Rahmeh, László Hangody.   

Abstract

Successful management of chondral and osteochondral defects of the weight-bearing joint surfaces has always been a challenge for orthopedic surgeons and rehabilitation specialists. Autologous osteochondral mosaic transplantation technique is one of the recently evolved methods to create hyaline or hyaline-like repair tissue in the pathologic area. Clinical evaluation, various imaging techniques, arthroscopy (second look), histological examination of biopsy samples, and measurements of cartilage mechanical properties are used to evaluate the merits of outcomes and quality of the transplanted cartilage. According to our investigations, good to excellent results were achieved in more than 92% of patients treated with femoral condylar implantations, 87% of those treated with tibial resurfacing, 79% of those treated with patellar and/or trochlear mosaicplasties, and 94% of those treated with talar procedures. Long-term donor-site discrepancies, assessed with use of the Bandi Score, showed that patients had 3% morbidity after mosaicplasty. Sixty-nine of 89 patients who were followed up with a second-look arthroscopy showed congruent gliding surfaces, histological evidence of the survival of the transplanted hyaline cartilage, and fibrocartilage filling of the donor sites. In a series of 831 consecutive patients, very few complications have been observed. These included 4 deep infections and 36 painful postoperative intra-articular bleedings. On the basis of these results and those of other similar studies, autologous osteochondral mosaicplasty appears to be a promising alternative for the treatment of small- and medium-sized focal chondral and osteochondral defects of the weight-bearing surfaces of the knee and other weight-bearing synovial joints.

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Year:  2006        PMID: 17063836     DOI: 10.2519/jospt.2006.2182

Source DB:  PubMed          Journal:  J Orthop Sports Phys Ther        ISSN: 0190-6011            Impact factor:   4.751


  27 in total

1.  Clinical and MRI evaluation of medium- to long-term results after autologous osteochondral transplantation (OCT) in the knee joint.

Authors:  L Zak; I Krusche-Mandl; S Aldrian; S Trattnig; S Marlovits
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-01-23       Impact factor: 4.342

2.  Characterization of adipose tissue-derived stromal vascular fraction for clinical application to cartilage regeneration.

Authors:  Yeonsue Jang; Yong Gon Koh; Yun-Jin Choi; Sung-Hwan Kim; Dong Suk Yoon; Moses Lee; Jin Woo Lee
Journal:  In Vitro Cell Dev Biol Anim       Date:  2014-11-01       Impact factor: 2.416

3.  CaAlg hydrogel containing bone morphogenetic protein 4-enhanced adipose-derived stem cells combined with osteochondral mosaicplasty facilitated the repair of large osteochondral defects.

Authors:  Linxin Chen; Yuanyuan Shi; Xin Zhang; Xiaoqing Hu; Zhenxing Shao; Linghui Dai; Xiaodong Ju; Yingfang Ao; Jianquan Wang
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2019-03-28       Impact factor: 4.342

4.  Comparison of chondral versus osteochondral lesions of the talus after arthroscopic microfracture.

Authors:  Hyeong-Won Park; Keun-Bae Lee
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2014-05-20       Impact factor: 4.342

Review 5.  Mesenchymal stem cells as a potent cell source for articular cartilage regeneration.

Authors:  Mohamadreza Baghaban Eslaminejad; Elham Malakooty Poor
Journal:  World J Stem Cells       Date:  2014-07-26       Impact factor: 5.326

6.  Stimulation of chondrogenic differentiation of adult human bone marrow-derived stromal cells by a moderate-strength static magnetic field.

Authors:  Harsh D Amin; Mariea Alice Brady; Jean-Philippe St-Pierre; Molly M Stevens; Darryl R Overby; C Ross Ethier
Journal:  Tissue Eng Part A       Date:  2014-02-07       Impact factor: 3.845

7.  Fresh Osteochondral Allograft Transplantation for Fractures of the Knee.

Authors:  Guilherme C Gracitelli; Luis Eduardo Passarelli Tirico; Julie C McCauley; Pamela A Pulido; William D Bugbee
Journal:  Cartilage       Date:  2016-07-07       Impact factor: 4.634

8.  Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem cells, silk scaffolds and bioreactors.

Authors:  Alexander Augst; Darja Marolt; Lisa E Freed; Charu Vepari; Lorenz Meinel; Michelle Farley; Robert Fajardo; Nipun Patel; Martha Gray; David L Kaplan; Gordana Vunjak-Novakovic
Journal:  J R Soc Interface       Date:  2008-08-06       Impact factor: 4.118

9.  In Vivo Bioreactor Using Cellulose Membrane Benefit Engineering Cartilage by Improving the Chondrogenesis and Modulating the Immune Response.

Authors:  Xue Guang Li; In-Su Park; Byung Hyune Choi; Ung-Jin Kim; Byoung-Hyun Min
Journal:  Tissue Eng Regen Med       Date:  2020-03-19       Impact factor: 4.169

10.  Differential effects of tyrosine-rich amelogenin peptide on chondrogenic and osteogenic differentiation of adult chondrocytes.

Authors:  H D Amin; C R Ethier
Journal:  Cell Tissue Res       Date:  2015-09-25       Impact factor: 5.249

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