Literature DB >> 28345414

Fresh Osteochondral Allograft Transplantation for Fractures of the Knee.

Guilherme C Gracitelli1, Luis Eduardo Passarelli Tirico2, Julie C McCauley3, Pamela A Pulido3, William D Bugbee4.   

Abstract

Objective The purpose of this study was to evaluate functional outcomes and allograft survivorship among patients with knee fracture who underwent fresh osteochondral allograft (OCA) transplantation as a salvage treatment option. Design Retrospective analysis of prospectively collected data. Setting Department of Orthopaedic Surgery at one hospital. Patients Fresh OCAs were implanted for osteochondral lesions after knee fracture in 24 males and 15 females with an average age of 34 years. Twenty-nine lesions (74%) were tibial plateau fractures, 6 (15%) were femoral condyle fractures, and 4 (10%) were patella fractures. Main Outcome Measurements Clinical evaluation included modified Merle d'Aubigné-Postel (18-point), International Knee Documentation Committee, and Knee Society function scores, and patient satisfaction. Failure of OCA was defined as revision OCA or conversion to total knee arthroplasty (TKA). Results Nineteen of 39 knees (49%) had further surgery. Ten knees (26%) were considered OCA failures (3 OCA revisions, 6 TKA, and 1 patellectomy). Survivorship of the OCA was 82.6% at 5 years and 69.6% at 10 years. Among the 29 knees (74%) that had the OCA still in situ, median follow-up was 6.6 years. Pain and function improved from preoperative to latest follow-up; 83% of patients reported satisfaction with OCA results. Conclusion OCA transplantation is a useful salvage treatment option for osteochondral lesions caused by knee fracture. Although the reoperation rate was high, successful outcome was associated with significant clinical improvement.

Entities:  

Keywords:  functional outcomes; knee fracture; osteochondral allograft transplant; survivorship

Year:  2016        PMID: 28345414      PMCID: PMC5358831          DOI: 10.1177/1947603516657640

Source DB:  PubMed          Journal:  Cartilage        ISSN: 1947-6035            Impact factor:   4.634


  42 in total

1.  Fresh osteochondral allografts in the knee: comparison of primary transplantation versus transplantation after failure of previous subchondral marrow stimulation.

Authors:  Guilherme C Gracitelli; Gokhan Meric; Dustin T Briggs; Pamela A Pulido; Julie C McCauley; João Carlos Belloti; William D Bugbee
Journal:  Am J Sports Med       Date:  2015-04       Impact factor: 6.202

2.  Fresh osteochondral allografting for steroid-associated osteonecrosis of the femoral condyles.

Authors:  Simon Görtz; Allison J De Young; William D Bugbee
Journal:  Clin Orthop Relat Res       Date:  2010-02-09       Impact factor: 4.176

3.  Articular cartilage transplantation. Clinical results in the knee.

Authors:  C R Chu; F R Convery; W H Akeson; M Meyers; D Amiel
Journal:  Clin Orthop Relat Res       Date:  1999-03       Impact factor: 4.176

4.  Fresh osteochondral allografting of the femoral condyle.

Authors:  F R Convery; M H Meyers; W H Akeson
Journal:  Clin Orthop Relat Res       Date:  1991-12       Impact factor: 4.176

5.  Do fresh osteochondral allografts successfully treat femoral condyle lesions?

Authors:  Yadin D Levy; Simon Görtz; Pamela A Pulido; Julie C McCauley; William D Bugbee
Journal:  Clin Orthop Relat Res       Date:  2013-01       Impact factor: 4.176

6.  Autologous chondrocyte implantation for joint preservation in patients with early osteoarthritis.

Authors:  Tom Minas; Andreas H Gomoll; Shahram Solhpour; Ralf Rosenberger; Christian Probst; Tim Bryant
Journal:  Clin Orthop Relat Res       Date:  2009-08-04       Impact factor: 4.176

7.  Osteochondral allograft transplantation in the knee.

Authors:  William Bugbee; Marco Cavallo; Sandro Giannini
Journal:  J Knee Surg       Date:  2012-05       Impact factor: 2.757

Review 8.  Autologous chondrocyte implantation and anteromedialization in the treatment of patellofemoral chondrosis.

Authors:  Jack Farr
Journal:  Orthop Clin North Am       Date:  2008-07       Impact factor: 2.472

9.  Resurfacing of the knee with fresh osteochondral allograft.

Authors:  M H Meyers; W Akeson; F R Convery
Journal:  J Bone Joint Surg Am       Date:  1989-06       Impact factor: 5.284

10.  Osteochondral Allograft Transplantation for Knee Lesions after Failure of Cartilage Repair Surgery.

Authors:  Guilherme C Gracitelli; Gokhan Meric; Pamela A Pulido; Julie C McCauley; William D Bugbee
Journal:  Cartilage       Date:  2015-04       Impact factor: 4.634

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  6 in total

1.  A Radiographic Sizing Algorithm for Tibial Plateau Osteochondral Allografts.

Authors:  David P Trofa; William C Graham; Kirk A McCullough; Christian Lattermann; David C Flanigan; Keith T Corpus; Bryan M Saltzman; James E Fleischli; Dana P Piasecki
Journal:  Cartilage       Date:  2019-03-12       Impact factor: 4.634

2.  Tibial Plateau Cartilage Lesions: A Systematic Review of Techniques, Outcomes, and Complications.

Authors:  Heath P Melugin; Christopher D Bernard; Christopher L Camp; Michael J Stuart; Daniel B F Saris; Norimasa Nakamura; Aaron J Krych
Journal:  Cartilage       Date:  2019-06-16       Impact factor: 3.117

Review 3.  Large Osteochondral Allografts of the Knee: Surgical Technique and Indications.

Authors:  Gabriele Pisanu; Umberto Cottino; Federica Rosso; Davide Blonna; Antonio Giulio Marmotti; Corrado Bertolo; Roberto Rossi; Davide E Bonasia
Journal:  Joints       Date:  2018-03-13

Review 4.  Autologous costal chondral transplantation and costa-derived chondrocyte implantation: emerging surgical techniques.

Authors:  Youshui Gao; Junjie Gao; Hengyuan Li; Dajiang Du; Dongxu Jin; Minghao Zheng; Changqing Zhang
Journal:  Ther Adv Musculoskelet Dis       Date:  2019-09-23       Impact factor: 5.346

Review 5.  Patellofemoral Cartilage Repair.

Authors:  Alexandre Barbieri Mestriner; Jakob Ackermann; Andreas H Gomoll
Journal:  Curr Rev Musculoskelet Med       Date:  2018-06

6.  Metrics of OsteoChondral Allografts (MOCA) Group Consensus Statements on the Use of Viable Osteochondral Allograft.

Authors:  Simon Görtz; Suzanne M Tabbaa; Deryk G Jones; John D Polousky; Dennis C Crawford; William D Bugbee; Brian J Cole; Jack Farr; James E Fleischli; Alan Getgood; Andreas H Gomoll; Allan E Gross; Aaron J Krych; Christian Lattermann; Bert R Mandelbaum; Peter R Mandt; Raffy Mirzayan; Timothy S Mologne; Matthew T Provencher; Scott A Rodeo; Oleg Safir; Eric D Strauss; Christopher J Wahl; Riley J Williams; Adam B Yanke
Journal:  Orthop J Sports Med       Date:  2021-03-23
  6 in total

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