Literature DB >> 17061165

Aging of brain: role of estrogen.

M K Thakur1, P K Sharma.   

Abstract

The brain undergoes many structural and functional changes during aging. Some of these changes are regulated by estrogens which act mainly through their intracellular receptors, estrogen receptor ERalpha and ERbeta. The expression of these receptors is regulated by several factors including their own ligand estrogen, and others such as growth hormone and thyroid hormone. The levels of these factors decrease during aging which in turn influence estrogen signaling leading to alterations in brain functions. In the present paper, we review the effects of aging on brain structure and function, and estrogen action and signaling during brain aging. The findings suggest key role of estrogen in the maintenance of brain functions during aging.

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Year:  2006        PMID： 17061165     DOI： 10.1007/s11064-006-9191-y

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  121 in total

Review 1.  Estrogen actions in the central nervous system.

Authors:  B S McEwen; S E Alves
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2.  Organization of the cerebral cortex. III. A study of aging in the human cerebral cortex.

Authors:  H BRODY
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3.  Mitochondrial localization of estrogen receptor beta.

Authors:  Shao-Hua Yang; Ran Liu; Evelyn J Perez; Yi Wen; Stanley M Stevens; Thomas Valencia; Anne-Marie Brun-Zinkernagel; Laszlo Prokai; Yvonne Will; James Dykens; Peter Koulen; James W Simpkins
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-15       Impact factor: 11.205

4.  Estrogen modulates neuronal Bcl-xL expression and beta-amyloid-induced apoptosis: relevance to Alzheimer's disease.

Authors:  C J Pike
Journal:  J Neurochem       Date:  1999-04       Impact factor: 5.372

Review 5.  Estradiol is a protective factor in the adult and aging brain: understanding of mechanisms derived from in vivo and in vitro studies.

Authors:  P M Wise; D B Dubal; M E Wilson; S W Rau; M Böttner; K L Rosewell
Journal:  Brain Res Brain Res Rev       Date:  2001-11

Review 6.  Estrogen: a neuroprotective or proinflammatory hormone? Emerging evidence from reproductive aging models.

Authors:  Farida Sohrabji
Journal:  Ann N Y Acad Sci       Date:  2005-06       Impact factor: 5.691

Review 7.  Mechanisms of estrogen action.

Authors:  S Nilsson; S Mäkelä; E Treuter; M Tujague; J Thomsen; G Andersson; E Enmark; K Pettersson; M Warner; J A Gustafsson
Journal:  Physiol Rev       Date:  2001-10       Impact factor: 37.312

8.  Membrane estrogen receptors identified by multiple antibody labeling and impeded-ligand binding.

Authors:  T C Pappas; B Gametchu; C S Watson
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Review 9.  Nongenomic actions of steroid hormones.

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Review 9.  Age-associated Cognitive Decline: Insights into Molecular Switches and Recovery Avenues.

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  9 in total

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