Literature DB >> 17060359

Combining functional and linkage disequilibrium information in the selection of tag SNPs.

P C Sham1, S I Ao, J S H Kwan, P Kao, F Cheung, P Y Fong, M K Ng.   

Abstract

UNLABELLED: We have developed an online program, WCLUSTAG, for tag SNP selection that allows the user to specify variable tagging thresholds for different SNPs. Tag SNPs are selected such that a SNP with user-specified tagging threshold C will have a minimum R2 of C with at least one tag SNP. This flexible feature is useful for researchers who wish to prioritize genomic regions or SNPs in an association study. AVAILABILITY: The online WCLUSTAG program is available at http://bioinfo.hku.hk/wclustag/

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Year:  2006        PMID: 17060359     DOI: 10.1093/bioinformatics/btl532

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  5 in total

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  5 in total

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